Sort   by:  
 Page size 
ProteomicsIdentification of proteins specifically binding to ac4C RNA probes
As a newly identified mRNA modification, the regulation of ac4C remains largely unexplored. RNA-binding proteins (RBPs) that specifically binds to ac4C modification and mediate downstream cellular activities (readers) have not been reported yet. We synthesized acetylated and non-acetylated RNA probe...
ORGANISM(S): Homo sapiens (Human) 
2021-07-20 | PXD027014 | Pride
Rna pulldown Ac4c Acetylated rna probes 
TranscriptomicsPlatform comparison and transcription profiling of mixed tissue RNA samples formulated to contain different ratios of RNA for each of four rat tissues (brain, liver, kidney, and testes) on Affymetrix RAE230A, CodeLink UniSet Rat I, and Agilent G4130A rat oligonucleotide arrays
This experiment is a test of a reagent that can provide a basis for performance assessments on Affymetrix RAE230A, CodeLink UniSet Rat I, and Agilent G4130A rat oligonucleotide arrays. The reagent is a set of two mixed tissue RNA samples formulated to contain different ratios of RNA for each of f...
ORGANISM(S): Rattus norvegicus 
2010-03-30 | E-TABM-16 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human moderate stage Huntingdons patients reveals histones associated with downregulated genes are hypo-acetylated
Transcriptional dysregulation plays a major role in the pathology of Huntington's disease (HD). However, the mechanisms causing selective downregulation of genes remain unknown. Histones regulate chromatin structure and thereby control gene expression; recent studies have demonstrated a therapeutic ...
ORGANISM(S): Mus musculus 
2008-06-20 | E-GEOD-11358 | biostudies-arrayexpress
TranscriptomicsComparison of Microarray Synthesis with and without Incorporating Debranching/Capping Step via Gene Expression Analysis
Gene expression microarrays require synthesizing a vast number of unique 60mer high-fidelity DNA probes to achieve strong signal intensity and low background noise, which are essential for accurate data interpretation. Due to the high number of coupling cycles involved in the synthesis, these DNA pr...
ORGANISM(S): Homo sapiens 
2025-06-30 | E-MTAB-15163 | biostudies-arrayexpress
TranscriptomicsLoss of Hepatocyte-Nuclear-Factor-1α Impacts on Adult Mouse Intestinal Epithelial Cell Growth and Cell Lineages Differentiation
Although hepatocyte-nuclear-factor-1α (Hnf1α) is crucial for pancreas and liver functions, it is believed to play a limited functional role for intestinal epithelial functions. The aim of this study was to assess the consequences of abrogating Hnf1α on the maintenance of adult small intestinal epit...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-23040 | biostudies-arrayexpress
TranscriptomicsHepatocyte-nuclear-factor-4a promotes gut neoplasia in mice and protects against the production of reactive oxygen species
Hepatocyte-nuclear-factor-4? (??Hnf4?) is a transcription factor that controls epithelial cell polarity and maturation during embryogenesis. Hnf4? conditional deletion during post-natal development results in minor consequences on intestinal epithelium integrity but promotes activation of the Wnt/...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-20968 | biostudies-arrayexpress
TranscriptomicsL1_20dC_0hrs_post-L1_N2_tiling_array
modENCODE_submission_484 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23270 | biostudies-arrayexpress
Transcriptomicssoma-only_mid-L4_25dC_36hrs_post-L1_JK1107_tiling_array
modENCODE_submission_485 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23271 | biostudies-arrayexpress
Transcriptomicsmid-L2_polA_enriched_20dC_14hrs_post-L1_N2_tiling_array
modENCODE_submission_477 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23266 | biostudies-arrayexpress
Transcriptomicsearly_embryo_20dC_0-4hrs_post-fertilization_N2_tiling_array
modENCODE_submission_476 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23265 | biostudies-arrayexpress
Sort   by:  
 Page size