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Quorum sensing (QS) is a mechanism of bacterial gene regulation in response to increases in population density. Production of small molecule QS signals, their accumulation within a diffusion-limited environment and their binding to the LuxR-type receptor trigger QS-controlled gene regulatory casca...
ORGANISM(S): Pseudomonas aeruginosa 
Macroautophagy (hereafter autophagy) is the major pathway by which macromolecules and organelles are degraded. Autophagy is regulated by the mTOR signaling pathway, which is the focal point for integration of metabolic information, with mTORC1 playing a central role in balancing biosynthesis and cat...
ORGANISM(S): Mus musculus 
Quorum sensing is a term used to describe cell-to-cell communication that allows cell density-dependent gene expression. Many Gram-negative bacteria use acyl-homoserine lactone (acyl-HSL) synthases to generate fatty acyl-HSL quorum sensing signals, which function with signal receptors to control exp...
ORGANISM(S): Rhodopseudomonas palustris CGA009 
The marine bacterium Phaeobacter inhibens produces tropodithietic acid (TDA), a broad-spectrum antibiotic and anticancer agent. TDA allows P. inhibens to antagonize other bacteria, including several pathogens, and eukaryotes. Since recently antibiotics are also discussed to function as intermicrobia...
ORGANISM(S): Phaeobacter inhibens 
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism
Homeostatic proliferation, driven by cytokines including IL-7, maintains stable T cell populations over time and expands these during lymphopenia, for example following stem cell transplantation. Yet, impaired T cell expansion in this context is associated with diminished immune protection, whilst e...
ORGANISM(S): Human 
2024-11-27 | MSV000096546 | MassIVE
Quorum sensing in Burkholderia cenocepacia H111 involves two signalling systems that depend on different signal molecules, namely N-acyl homoserine lactones (AHLs) and the diffusible signal factor cis-2-dodecenoic acid (BDSF). Previous studies have shown that AHLs and BDSF control similar phenotypic...
ORGANISM(S): Burkholderia cenocepacia H111 
Macroautophagy (hereafter autophagy) is the major pathway by which macromolecules and organelles are degraded. Autophagy is regulated by the mTOR signaling pathway, which is the focal point for integration of metabolic information, with mTORC1 playing a central role in balancing biosynthesis and cat...
ORGANISM(S): human gammaherpesvirus 4 JC polyomavirus Human gammaherpesvirus 8 Betapolyomavirus macacae Rattus norvegicus Homo sapiens Mus musculus Human alphaherpesvirus 1 Human betaherpesvirus 5 Human immunodeficiency virus 1 Betapolyomavirus hominis 
2015-08-03 | GSE60452 | GEO
A new adipocyte-specific long non-coding RNA engages impaired fatty acid sensing and dyslipidaemia in obese subjects (microarray)
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