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TranscriptomicsThe pH-sensing receptor OGR1 improves barrier function of CaCo-2 cells and inhibits migration in an acidic environment
OGR1 is a pH-sensing G-protein coupled receptor involved in intestinal homeostasis and inflammation Proton activation of OGR1 increases barrier function in Caco2 cells Microarray profiling was performed on OGR1 stable overexpressing Caco-2 cells during acidic pH shift
ORGANISM(S): Homo sapiens 
2015-08-13 | E-GEOD-60294 | biostudies-arrayexpress
TranscriptomicsMycobacterium tuberculosis transcriptional responses to acidic pH and carbon source
The purpose of this study was to examine how Mtb integrates acidic pH and available carbon sources as environmental cues to regulate its metabolism and growth rate. RNA-seq transcriptional profiling of M. tuberculosis growing at acidic or neutral pH, in pyruvate or glycerol, was examined. These stu...
ORGANISM(S): Mycobacterium tuberculosis 
2014-07-07 | E-GEOD-52020 | biostudies-arrayexpress
GenomicsGrowth arrest of Mycobacterium tuberculosis in acidic environments enhances their survival of antibiotic treatment
Growth arrest of Mycobacterium tuberculosis in acidic environments enhances their survival of antibiotic treatment
PRJNA1289097 | ENA
TranscriptomicsTranscriptional profiling of M. tuberculosis CDC1551 wild type vs aprABC null, aprBC null, aprC null and phoP transposon mutants.
Following phagocytosis by macrophages, Mycobacterium tuberculosis (Mtb) senses the intracellular environment and remodels its gene expression for growth in the phagosome. Abramovitch et.al. in this current study identified an Acid and Phagosome Regulated (aprABC) locus that is unique to the Mtb comp...
ORGANISM(S): Mycobacterium tuberculosis 
2011-07-09 | E-GEOD-22854 | biostudies-arrayexpress
GenomicsDomas Crater - Acidic hot springs
Domas Crater - Acidic hot springs Raw sequence reads
PRJNA1118357 | ENA
UnknownTranscriptome Analysis of the Nematode Caenorhabditis elegans in Acidic Stress Environments.
Not available
S-EPMC7511720 | biostudies-literature
TranscriptomicsGrowth arrest of Mycobacterium tuberculosis in acidic environments enhances their survival of antibiotic treatment
The ability of Mycobacterium tuberculosis (Mtb) bacilli to adapt to host microenvironments by changing growth behaviors promotes population-level survival against host and drug stressors. However, we have a poor understanding of how Mtb’s growth behaviors change at a single-cell level as the populat...
ORGANISM(S): Mycobacterium tuberculosis 
2026-05-28 | GSE302156 | GEO
UnknownCollective condensation and auto-aggregation of Escherichia coli in uniform acidic environments.
Not available
S-EPMC11339372 | biostudies-literature
GenomicsDomas Crater - Acidic hot springs
Metagenomic analysis of hotspring water samples from Domas Crater - Acidic Hot springs, Indonesia
PRJNA1117210 | ENA
UnknownEscherichia Coli Increases its ATP Concentration in Weakly Acidic Environments Principally through the Glycolytic Pathway.
Not available
S-EPMC7563387 | biostudies-literature
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