Acrb - OmicsDI

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CHEBI ID

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CHEBI:89019 (1)
CHEBI:89016 (1)

Metabolite Name

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Eriojaposide B (2)
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N-acetyl-alpha-D-galactosamine 1-phosphate (2)
Didemethylcitalopram (2)
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Dicyclohexylamine (2)
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Isopyridoxal (2)

First Public Date

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Classification

bacteria (6)

Study type

Transcription profiling by array (160)
RNA-seq of coding RNA (45)
Other (8)
RNA-seq of coding RNA from single cells (4)
Animal - High-throughput sequencing (3)
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Transcription profiling by SAGE (1)
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ChIP-chip by array (1)
CLIP-seq (1)
MicroRNA profiling by high throughput sequencing (1)
MicroRNA profiling by array (1)
Genotyping by high throughput sequencing (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2014 (50)
2021 (46)
2010 (36)
2022 (34)
2013 (34)
2025 (33)
2012 (33)
2015 (32)
2020 (31)
2016 (30)
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2009 (27)
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2000 (1)

Lab affiliation

Associate professor, School of Biosciences, University of Southampton, England (1)
Department of Chemistry, King's College London (1)
Department of Chemisty, Redaing Group, King's College London (1)
Molecular Proteomics Laboratory (MPL) Biologisch-Medizinisches Forschungszentrum (BMFZ) Heinrich-Heine-Universität Düsseldorf (1)
Weizmann Institute of Science Department of Biomolecular Sciences Faculty of Biochemistry (1)
biOMICS Mass Spectrometry Facility Department of Biomedical Science Centre for Membrane Interactions and Dynamics (CMIAD) E-04, Florey building Firth Court, Western Bank The University of Sheffield Sheffield S10 2TN United Kingdom (1)

Tags

pathogen (6)
pathogen:bacterium (6)
xref:ArrayExpress:E-MTAB-5573 (1)
xref:PubMed:33593966 (1)
xref:PubMed:38593161 (1)
xref:PubMed:29150513 (1)

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Transcription profiling of Salmonella enterica serovar Typhimurium to investigate the effects of acrB duisruption

Analysis of effect of disruption of acrB on the transcriptome of Salmonella enterica serovar Typhimurium

ORGANISM(S): Salmonella typhimurium

2009-06-03 | E-MEXP-1981 | biostudies-arrayexpress

Hydrogen/deuterium exchange mass spectrometry of AcrB in MSP nanodiscs

Investigating the inhibition of AcrB by MBX-3756 within a lipid environment using HDX-MS

ORGANISM(S): Escherichia coli

2025-07-24 | PXD066556 | Pride

HDX-MS reveals the perturbed structural dynamics underlie inhibition and altered specificity of the multidrug efflux pump AcrB

Perturbed structural dynamics underlie inhibition and altered specificity of the multidrug efflux pump AcrB

ORGANISM(S): Escherichia coli

2020-10-07 | PXD019047 | Pride

Acrb Hdx-ms Membrane proteins Multi-drug efflux pumps

RNA-seq of wild-type Salmonella Typhimurium SL1344 and its AcrB D408A mutant

The aim of this experiment was to determine the changes in transcription caused by the loss of efflux function of AcrB. Three biological replicates per strain were grown in MOPS minimal medium to an OD600 of 0.6. Total RNA was extracted and DNase-treated. The samples were sent to BGI, Hong Kong for ...

ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344

2017-06-29 | E-MTAB-5573 | biostudies-arrayexpress

RNA-seq of Escherichia coli MG1655 and Salmonella Typhimurium SL1344 wild-types and their respective AcrB D408A mutants in LB broth, in stationary phase

This experiment was designed to find differences and similarities between the loss-of-AcrB-efflux-function mutants of two Enterobacterales, in stationary phase. Cultures were grown in LB broth for 10 hours. Four biological replicates per strain were analysed.

ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium

2021-03-04 | E-MTAB-8352 | biostudies-arrayexpress

RNA-seq of wild-type Salmonella Typhimurium SL1344 and its AcrB D408A mutant

PRJEB21580 | ENA

Energy coupling mechanisms of AcrB-like RND transporters.

Not available

S-EPMC5719797 | biostudies-literature

Unfolding study of a trimeric membrane protein AcrB.

Not available

S-EPMC4088973 | biostudies-literature

Functional relevance of AcrB Trimerization in pump assembly and substrate binding.

Not available