Sort   by:  
 Page size 
ProteomicsDNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs
DNA interstrand crosslinks (ICLs) are highly cytotoxic lesions that block essential cellular processes like replication and transcription. Endogenous ICLs can be induced by reactive aldehydes produced during normal cellular metabolism. Defective repair of these aldehyde-induced ICLs is associated wi...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2025-09-29 | PXD062134 | Pride
Acrolein-icl Fa pathway Acetaldehyde-icl Polymerase kappa Translesion synthesis 
ProteomicsDNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs
DNA interstrand crosslinks (ICLs) are highly cytotoxic lesions that block essential cellular processes like replication and transcription. Endogenous ICLs can be induced by reactive aldehydes produced during normal cellular metabolism. Defective repair of these aldehyde-induced ICLs is associated wi...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2025-09-29 | PXD066315 | Pride
Dna polymerase kappa Acrolein-icl Translesion synthesis Fanconi anemia pathway Acetaldehyde-icl 
UnknownDNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs.
Not available
S-EPMC12455607 | biostudies-literature
Sort   by:  
 Page size