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ProteomicsActb knockout in primary mouse embryonic fibroblasts LC-MS/MS
The cytoplasmic actin proteins, beta- and gamma-actin, are 99% identical but perform non-redundant functions. Genes encoding the cytoplasmic actins, Actb and Actg1, respectively, are less similar but still share 89% of their nucleotide sequences. Knockout (KO) of Actb by deletion of first coding exo...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-19 | PXD039786 | Pride
Actb Actin Actin isoforms Beta actin 
GenomicsNext-generation sequencing analysis of chemically induced neurons from wild type (WT), Actb+/- (HET) and Actb-/- (KO) mouse embryonic fibroblasts (MEFs)
Next-generation sequencing analysis of chemically induced neurons from wild type (WT), Actb+/- (HET) and Actb-/- (KO) mouse embryonic fibroblasts (MEFs)
PRJNA453803 | ENA
GenomicsACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells
ACTB is a cytoskeletal protein involved in intracellular trafficking. In recent years, it has become evident that, in addition to its established roles in these compartments, ACTB also participates in the regulation of transcription. However, the molecular mechanisms underlying this function remain ...
ORGANISM(S): Homo sapiens 
2026-01-29 | GSE308375 | GEO
TranscriptomicsACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells
ACTB is a cytoskeletal protein involved in intracellular trafficking. In recent years, it has become evident that, in addition to its established roles in these compartments, ACTB also participates in the regulation of transcription. However, the molecular mechanisms underlying this function remain ...
ORGANISM(S): Homo sapiens 
2026-01-29 | GSE308376 | GEO
GenomicsTFAM binding analysis at mitochondrial genome between Wild Type (Wt) and Actb-/- (KNO) Mouse Embryonic Fibroblast
Using Chromatin-immunoprecipitation and NGS, we investigated the binding of TFAM protein at mitochondrial genome between Actb+/+ Wild Type (WT) and Actb-/- (KO) Mouse Embryonic Fibroblast
ORGANISM(S): Mus musculus 
2018-01-24 | GSE109532 | GEO
UnknownPseudogenes as weaknesses of ACTB (Actb) and GAPDH (Gapdh) used as reference genes in reverse transcription and polymerase chain reactions.
Not available
S-EPMC3425558 | biostudies-literature
GenomicsTFAM binding analysis at mitochondrial genome between Wild Type (Wt) and Actb-/- (KNO) Mouse Embryonic Fibroblast
TFAM binding analysis at mitochondrial genome between Wild Type (Wt) and Actb-/- (KNO) Mouse Embryonic Fibroblast
PRJNA431307 | ENA
UnknownPost-zygotic ACTB mutations underlie congenital smooth muscle hamartomas.
Not available
S-EPMC7943230 | biostudies-literature
TranscriptomicsNext-generation sequencing analysis of chemically induced neurons from wild type (WT), Actb+/- (HET) and Actb-/- (KO) mouse embryonic fibroblasts (MEFs)
Purpose: The goals of this study are to use NGS to perform transcriptome profiling (RNA-seq) to find the difference of the transcriptomes of chemically induced neurons from wild type (WT), Actb+/- (HET) and Actb-/- (KO) mouse embryonic fibroblasts. Methods: MEFs were reprogramed into neurons by smal...
ORGANISM(S): Mus musculus 
2018-04-27 | GSE113733 | GEO
GenomicsACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells
ACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells
PRJNA1330305 | ENA
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