Acute myocardial infarction

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Tissue

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Liver (1)
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Disease

Acute myocardial infarction (7)
Cardiovascular system disease (5)
Myocardial ischemia (5)
Myocardial infarction (4)
Ischemic (1)
Ischaemia reperfusion injury (1)
Coronary artery disease (1)
Normal (1)
Advanced gastrointestinal cancers (1)
Gastric cancer (1)
Inflammatory Bowel Diseases (1)
Heart disease (1)

Technology Type

Mass Spectrometry (37)
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Mass spectrometry (9)
Bottom-up proteomics (9)
Affinity purification coupled with mass spectrometry proteomics (4)
Data-independent acquisition (4)
Data-dependent acquisition (3)
Gel-based experiment (2)
SWATH MS (2)
Illumina HiSeq 2000 (1)
NMR spectroscopy assay (1)
NMR spectroscopy (1)
ESI (1)
Affinity proteomics (1)
DiaPASEF (1)
MSE (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (12)
Illumina HiSeq 4000 (6)
Liquid Chromatography MS - positive - reverse phase (6)
Q Exactive (4)
Liquid Chromatography MS - negative - reverse phase (4)
Single nuclei were captured using the 10x Genomics Chromium Controller. (2)
NextSeq 2000 (2)
NextSeq 500 (2)
MALDI Synapt G2-S HDMS (2)
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- (1)
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Ion Torrent S5 XL (1)
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6545 Q-TOF LC/MS (1)
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Q-Exactive HF (1)
QTRAP 6500+ (1)
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Direct infusion MS - positive (1)
Bruker (1)
Nuclear Magnetic Resonance (NMR) - (1)
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Publication Date

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2014 (19)
2010 (15)
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2007 (5)
2006 (4)
2004 (1)

CHEBI ID

CHEBI:28044 (5)
CHEBI:27468 (5)
CHEBI:30769 (5)
CHEBI:24813 (4)
CHEBI:16196 (4)
CHEBI:17568 (4)
CHEBI:17015 (4)
CHEBI:16467 (4)
CHEBI:15428 (4)
CHEBI:15978 (4)
CHEBI:16737 (4)
CHEBI:15603 (4)
CHEBI:28865 (4)
CHEBI:17351 (4)
CHEBI:17368 (4)
CHEBI:32389 (3)
CHEBI:22470 (3)
CHEBI:64561 (3)
CHEBI:27570 (3)
CHEBI:30751 (3)
CHEBI:17234 (3)
CHEBI:28300 (3)
CHEBI:16708 (3)
CHEBI:48928 (3)
CHEBI:18009 (3)
CHEBI:27823 (3)
CHEBI:27266 (3)
CHEBI:17650 (3)
CHEBI:16359 (3)
CHEBI:16411 (3)

Metabolite Name

Ergothioneine (3)
Choline (3)
Cholic acid (3)
L-Arginine (3)
Uridine (3)
L-Leucine (3)
L-Phenylalanine (3)
6-Phospho-D-gluconate (2)
N6-Methyl-L-lysine (2)
L-Citrulline (2)
Arachidonate (2)
Betaine aldehyde (2)
Glycine (2)
Hercynine (2)
NADP+ (2)
NAD+ (2)
AMP (2)
ATP (2)
L-Alanine (2)
Cyclohexylamine (2)
Uracil (2)
Thymine (2)
Thiamine (2)
Dehydroepiandrosterone sulfate (2)
5-Hydroxyindoleacetate (2)
S-Adenosyl-L-homocysteine (2)
Pantothenate (2)
CDP-ethanolamine (2)
5-Methylcytosine (2)
D-Fructose 1,6-bisphosphate (2)

First Public Date

2025 (43)
2026 (37)
2024 (31)
2022 (27)
2023 (26)
2014 (19)
2021 (15)
2019 (14)
2020 (11)
2017 (10)
2018 (4)
2013 (4)
2015 (3)
2016 (2)

Modelling Approach

Ordinary differential equation model (1)

Study status

Ongoing (1)
Active, not recruiting (1)
Recruiting (1)

Lab affiliation

King's College London, British Heart Foundation Centre, School of Cardiovascular Medicine and Sciences, London, UK (2)
Odense University Hospital, Dept Clinical Biochemistry and Pharmacology, Odense, DK-5000, Denmark (2)
Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, 90089, USA Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine of USC, Los Angeles, CA, 90033, USA (1)
Analytical Biochemistry Global Research CSL (1)
Central Diagnostic Laboratory Maastricht University Medical Centre Maastricht, the Netherlands (1)
Charles Perkins Centre, University of Sydney (1)
Core Facility Proteomics, Department of Clinical Medicine, University Medical Center Goettingen, Germany (1)
Core Facilitz Proteomics, Department of Clinical Chemistry, University Medical Center Goettingen (1)
Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Denmark (1)
Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital; NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides; Key Laboratory of Molecular Cardiovascular Science, Ministry of Education; Beijing Key Laboratory of Cardiovascular Receptors Research; Haihe Laboratory of Cell Ecosystem. Beijing 100191, China. (1)
Department of Cardiology, Medical University Hospital, Heidelberg, Germany (1)
Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China (1)
Department of Medicine I (1)
Department of Molecular Cell Biology, Weizmann Institute of Science (1)
Department of Pharmacology, College of Basic Medical Sciences, Jilin University, Changchun, 130000, China (1)
Deutsches Herzzentrum der Charité – Medical Heart Center of Charité and German Heart Institute Berlin, Department of Cardiothoracic and Vascular Surgery, 13353 Berlin, Germany (1)
ITQB-NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. Da República, 2780-157 Oeiras, Portugal;iBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901, Oeiras , Portugal (1)
ITQB-NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. da República, 2780-157, Oeiras, Portugal; iBET- Instituto de Biologia Experimental e Tecnológica, Apartado 12 2780-901 Oeiras, Portugal (1)
Institute for Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt am Main, Germany (1)
Institute of Cellular Biology and Pathology (1)
Institute of Cellular Biology and Pathology "N. Simionescu", Proteomics Department, Bucharest, Romania (1)
Jagiellonian University Medical College (1)
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany (1)
National Heart and Lung Institute, Imperial College London, United Kingdom (1)
National Metrology Institute of TURKEY (1)
Physiology, NUI Galway (1)
Professor of Vascular Biology Director, Cardiovascular Research Laboratory Division of Cardiology, Pulmonology, and Vascular Medicine University Hospital and Medical Faculty Heinrich-Heine-University Düsseldorf Moorenstr. 5, Mailbox 1125 40225 Düsseldorf, Germany (1)
Proteomics Core of Bioscience Research Centre, School of Biological Sciences, Nanyang Technological University, Singapore (1)
Rappaport Faculty of Medicine Technion, Israel Institute of Technology, Haifa, Israel (1)
SBBS, Conway Institute, UCD, Belfield, Dublin (1)

Keyword

Lonsurf (1)
Oxaliplatin (1)

IsPrivate

False (1)

Modification

15.994915 (1)
57.021464 (1)

Study type

Transcription profiling by array (113)
RNA-seq of coding RNA from single cells (13)
RNA-seq of coding RNA (10)
ChIP-chip by tiling array (2)
Animal - Single-cell sequencing (2)
Methylation profiling by high throughput sequencing (2)
Interventional (2)
Single-nucleus ATAC-seq (1)
Unknown experiment type (1)
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Bisulfite-seq (1)
Hi-C (1)
Other (1)
Single nucleus RNA sequencing (1)
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RNA-seq of non coding RNA (1)
Observational (1)

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2003 (6)
2002 (5)
1999 (3)
2004 (2)
2001 (2)
2000 (2)

Location

Australia (1)
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NMR-based metabolomics identifies patients at high risk of death within two years after acute myocardial infarction in the AMI-Florence II cohort

Risk stratification and management of acute myocardial infarction patients continue to be challenging despite considerable efforts made in the last decades by many clinicians and researchers. The aim of this study was to investigate the metabolomic fingerprint of acute myocardial infarction using nu...

2018-10-02 | MTBLS395 | MetaboLights

Post Acute Myocardial Infarction Left Ventricular Remodeling Bio marker Analysis (PAMILA)

Not available

ORGANISM(S): Homo sapiens

ST001908 | MetabolomicsWorkbench

Targeted metabolomic profiling of myocardial remodeling after STEMI

Early detection of myocardial remodeling is essential for optimizing outcomes in patients with ST-segment elevation myocardial infarction (STEMI). However, reliable biomarkers for predicting STEMI myocardial remodeling remain scarce.

Targeted metabolomic profiling was performed on plasma ...

2025-09-02 | MTBLS10634 | MetaboLights

Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction.

Recent technological advances have made transcriptome sequencing (RNA-seq) possible in cells with low RNA copy number including platelets. Resulting studies have used RNA-seq in platelets isolated from healthy individuals to characterize the platelet transcriptome. However, platelets, possibly throu...

ORGANISM(S): Homo sapiens

2015-09-15 | E-GEOD-65705 | biostudies-arrayexpress

miRNA profiling in the plasma of patients with acute myocardial infarction (AMI)

Studies of miRNA profiling in the plasma of AMI patients with Left ventricular end diastolic volume (LVEDV) increase or LVEDV decrease between discharge and follow-up Venous blood was collected in citrated tubes prior discharge. Plasma was harvested by centrifugation and stored at -80Â°C until assay...

ORGANISM(S): Homo sapiens

2013-05-14 | E-GEOD-34571 | biostudies-arrayexpress

A Comparison of the Efficacy of Transplantation of Bone Marrow Derived Mesenchymal Stem Cells and Unrestricted Somatic Stem Cells on Outcome After Acute Myocardial Infarction

Unrestricted Somatic Stem Cells (USSC) are a cell population derived from umbilical cord blood. They have been shown to have greater plasticity than mesenchymal stem cells, and are being investigated as a therapeutic option for many disease states, including cardiovascular disease.

In this st...

ORGANISM(S): Homo sapiens

2012-08-24 | E-MEXP-3638 | biostudies-arrayexpress

myocardial infarction in Reg3beta knock-out mice

Affymetrix microarray analysis of molecular changes after myocardial infarction. Samples of heart tissue were analyzed after myocardial infarction from WT and reg3beta knock-out mice. Samples from scar tissue and samples adjacent to the scar were analyzed. In the experiment we primarily compared inf...

ORGANISM(S): Mus musculus

2015-06-29 | E-MTAB-2561 | biostudies-arrayexpress

Altered expression of microRNAs in the myocardium of rats with acute myocardial infarction

MicroRNAs are important cellular components and their dysfunctions are associated with various disease. Acute myocardial infarction (AMI) is one of the most serious cardiovascular diseases. Although several miRNAs have been reported to be associated with AMI, more novel miRNAs are needed to be inves...

ORGANISM(S): Mus musculus

2010-04-22 | E-GEOD-19695 | biostudies-arrayexpress

Single-cell RNA sequencing of bone marrow HSPCs isolated from patients after myocardial infarction and control patients

This experiment focused on studying the impact of myocardial infarction on bone marrow HSPCs (LineageNeg, CD38Neg, CD34Pos). Human sternal bone marrow was extracted from the sternum of acute patients who had undergone myocardial infarction (n = 6), as well as from control patients (n = 7), during su...

ORGANISM(S): Homo sapiens

2025-02-05 | E-MTAB-13509 | biostudies-arrayexpress

miRNA dysregulation in AMI serum

To detect the dysregulated miRNAs in the serum of acute myocardial infarction patients.

ORGANISM(S): Homo sapiens

2012-04-30 | E-MEXP-3578 | biostudies-arrayexpress

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