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GenomicsMortierella sp. AD 185 isolate:AD 185
Mortierella sp. AD 185 Transcriptome - AD 185
PRJNA582288 | ENA
TranscriptomicsTranscriptional profiles of Ad-F3 and Ad-F7 transduced macrophages
To identify genes that may regulate distinct or overlapping functions of IRF-3 and IRF-7, primary human macrophage preparations were transduced with adenoviral vectors: Ad-GFP (control), Ad-F3 (expressing the active form of IRF-3, IRF-3 5D), or Ad-F7 (expressing the active form of IRF-7, IRF-7 D247-...
ORGANISM(S): Homo sapiens 
2008-11-29 | E-GEOD-11926 | biostudies-arrayexpress
TranscriptomicsGene expression data from temporal cortex of young adult, old and AD-like Microcebus murinus
Aging is the primary risk factor of neurodegenerative disorders such as Alzheimer's disease (AD). However, the molecular events occurring during brain aging are extremely complex and still largely unknown. For a better understanding of these age-associated modifications, animal models as close as po...
ORGANISM(S): Microcebus murinus 
2011-04-01 | E-GEOD-21779 | biostudies-arrayexpress
TranscriptomicsExpression data from non-demented controls (NDCs) and Alzheimer's disease (AD) patients
AD is the leading cause of dementia in the elderly. However, disease etiology is still practically unknown. To gain insight into the molecular mechanisms underlying this disease we used the Affymetrix exon arrays to profile the alternative splicing landscape of human entorhinal cortex samples from A...
ORGANISM(S): Homo sapiens 
2012-09-06 | E-GEOD-26972 | biostudies-arrayexpress
ProteomicsCandidate disease progression biomarkers in AD
Cross-sectional and longitudinal Analysis of CSF from controls and cases with AD
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-07-15 | MSV000079192 | MassIVE
TranscriptomicsInduced pluripotent stem cell-derived neurons from a sporadic Alzheimer disease donor as a model for investigating disease mechanisms
Gene expression analysis of control fibroblasts (NFH2), one AD-derived fibroblasts (NFH-46), NFH2-derived control-iPS cells (OiPS3, OiPS6), NFH46-derived AD-iPS cells (iPS5 and iPS 26B), hESCs (H1 and H9). Total mRNA obtained from AD fibroblasts (NFH-46) and control fibroblasts (NFH-2), from plurip...
ORGANISM(S): Homo sapiens 
2015-04-21 | E-GEOD-42492 | biostudies-arrayexpress
ProteomicsAge-dependent changes in phosphorylation of signaling molecules in brain tissues of Alzheimer's disease (AD) model mice
To demonstrate the utility of the newly developed dendron-coated phosphokinase antibody array(DPA) in which the antibodies are immobilized on a dendron-coated glass slide, the phosphorylation profiles of brain tissue samples obtained from Alzheimer's disease (AD) model mice were generated. The phosp...
ORGANISM(S): Mus musculus 
2015-02-24 | E-GEOD-55452 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Alzheimers disease patients to identify genes regulating synaptic function and neuroplasticity in incipient AD
In Alzheimer's disease (AD), early deficits in learning and memory are a consequence of synaptic modification which are likely induced by toxic beta-amyloid oligomers (dAbeta). To identify molecular targets downstream of dAbeta binding we prepared synaptoneurosomes from frontal cortex of control a...
ORGANISM(S): Homo sapiens 
2009-01-17 | E-GEOD-12685 | biostudies-arrayexpress
GenomicsMartelella sp. AD-3
Martelella sp. AD-3 Genome sequencing
PRJNA310308 | ENA
TranscriptomicsGenome-wide profiling of altered gene expression in the neocortex of Alzheimer's disease (gene level)
We investigated genome-wide gene alterations in the temporal cortex of a well-characterized cohort of AlzheimerM-bM-^@M-^Ys disease (AD) patients using Affymetrix exon arrays. The AD patients and controls are subjects originally recruited into OPTIMA (Oxford Project to Investigate Memory and Ageing)...
ORGANISM(S): Homo sapiens 
2012-04-12 | E-GEOD-37263 | biostudies-arrayexpress
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