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ProteomicsComparative analysis of ChAdOx1 nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines
Vector-based SARS-CoV-2 vaccines such as AstraZeneca's ChAdOx1 nCoV-19 have been associated with vaccine-induced thrombosis (TTS/VITT). We studied ChAdOx1 nCov-19 (AstraZeneca) and Ad26.COV2.S (Johnson & Johnson) and compared the vaccines using proteomics with mass spectrometric measurements. We cou...
ORGANISM(S): Homo sapiens (Human) 
2023-05-04 | PXD027344 | Pride
Ad26.cov2.s Sars-cov-2 Vector vaccines Chadox1 
GenomicsAd26.COV2.S Prevents SARS-CoV-2 Induced Pathways of Inflammation and Thrombosis in Hamsters
Ad26.COV2.S Prevents SARS-CoV-2 Induced Pathways of Inflammation and Thrombosis in Hamsters
PRJNA807676 | ENA
TranscriptomicsA homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2-specific immune responses in rhesus macaques
Ad26.COV2.S has demonstrated durability and clinical efficacy against symptomatic COVID-19 in humans. In this study, we report the correlates of durability of humoral and cellular immune responses in 20 rhesus macaques immunized with single-shot Ad26.COV2.S and the immunogenicity of a booster shot a...
ORGANISM(S): Macaca mulatta 
2022-02-10 | GSE193264 | GEO
TranscriptomicsAd26.COV2.S Prevents SARS-CoV-2 Induced Pathways of Inflammation and Thrombosis in Hamsters
Syrian golden hamsters exhibit features of severe disease after SARS-CoV-2 challenge and are therefore useful models of COVID-19 pathogenesis and prevention with vaccines. Recent studies have shown that SARS-CoV-2 infection stimulates type I interferon, myeloid, and inflammatory signatures similar t...
ORGANISM(S): Mesocricetus auratus 
2022-03-26 | GSE196893 | GEO
UnknownSafety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants.
Not available
S-EPMC11008839 | biostudies-literature
UnknownSafety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants.
Not available
S-EPMC10690356 | biostudies-literature
GenomicsA homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2-specific immune responses in rhesus macaques
A homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2-specific immune responses in rhesus macaques
PRJNA795508 | ENA
UnknownImmunogenicity and Reactogenicity of Vaccine Boosters after Ad26.COV2.S Priming.
Not available
S-EPMC8796791 | biostudies-literature
UnknownB cell somatic hypermutation following COVID-19 vaccination with Ad26.COV2.S.
Not available
S-EPMC11035370 | biostudies-literature
UnknownDetection of pre-existing neutralizing antibodies against Ad26 in HIV-1-infected individuals not responding to the Ad26.COV2.S vaccine.
Not available
S-EPMC10106868 | biostudies-literature
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