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TranscriptomicsIntegration of BRCA1-mediated miRNA and mRNA signatures reveal miR-146a, miR-99b and miR-205 regulation of the TRAF2 and NFkB pathways (mRNA dataset)
BRCA1 deregulation is a frequent event in the pathogenesis of breast as well as other cancers. In addition to the DNA repair functions of BRCA1, it is involved in a wide range of cellular processes such as cell cycle, chromatin remodeling or transcription. However, the molecular events underlying BR...
ORGANISM(S): Homo sapiens 
2011-12-24 | E-GEOD-30821 | biostudies-arrayexpress
TranscriptomicsIntegration of BRCA1-mediated miRNA and mRNA signatures reveal miR-146a, miR-99b and miR-205 regulation of the TRAF2 and NFkB pathways
This SuperSeries is composed of the following subset Series: GSE30763: Integration of BRCA1-mediated miRNA and mRNA signatures reveal miR-146a, miR-99b and miR-205 regulation of the TRAF2 and NFkB pathways (miRNA dataset) GSE30821: Integration of BRCA1-mediated miRNA and mRNA signatures reveal miR-1...
ORGANISM(S): Homo sapiens 
2011-12-24 | E-GEOD-30822 | biostudies-arrayexpress
TranscriptomicsMicroarray expression analysis of hearts of zebrafish tremblor mutants at 48 hpf compared to wild-type siblings.
Zebrafish ncx1h (also known as slc8a1a) encodes a cardiac specific sodium-calcium exchanger 1 (NCX1h), a primary Ca 2+ efflux effector in cardiomyocytes. The zebrafish tremblor (tre) mutant lacks functional NCX1h and, consequentially, cyclic Ca2+ transients are abolished. In this study, we investiga...
ORGANISM(S): Danio rerio 
2017-09-20 | E-MTAB-5850 | biostudies-arrayexpress
TranscriptomicsPortrait of early-onset breast cancer in Brazilian patients: germline mutation screening of BRCA1, BRCA2 and TP53 genes and tumor expression profiling
Differentially expressed genes between BRCA1/BRCA2 negative and positive mutation driven-tumors. Screening for germline mutations was performed in a cohort of 55 patients under the age of 35 years in the BRCA1, BRCA2, CHEK2 (c.del1,100C) and TP53 genes, and the respective tumors were investigated re...
ORGANISM(S): Homo sapiens 
2013-04-09 | E-GEOD-37126 | biostudies-arrayexpress
TranscriptomicsCpG islands Methylation Profiling by DMH in Epithelial Ovarian Cancer: Screening Set
We have systematically profiled DNA methylation at promoter CpG islands (CGIs) in ovarian cancer. Epithelial ovarian tumours, excluding mucinous and clear cell cancers, prospectively collected through a cohort study, were analyzed by differential methylation hybridization (DMH) (Nouzova M et al, 200...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-23240 | biostudies-arrayexpress
ProteomicsPrimary human fibroblasts proteome response to an icMERS coronavirus
Proteomics data from cell culture; Treated with wild-type MERS-CoV, MERS-CoV mutants and mockulum; 5 biological replicates; time points 0, 12, 24, 36 & 48 h
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Middle East Respiratory Syndrome-related Coronavirus (ncbitaxon:1335626) 
2016-08-05 | MSV000080028 | MassIVE
ProteomicsPrimary human microvascular endothelial cells proteome response to an icMERS coronavirus
Proteomics data from cell culture; Treated with wild-type MERS-CoV, MERS-CoV mutants and mockulum; 5 biological replicates; time points 0, 12, 24, 36 & 48 h
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Middle East Respiratory Syndrome-related Coronavirus (ncbitaxon:1335626) 
2016-08-05 | MSV000080029 | MassIVE
ProteomicsHuman Ebola Virus Disease Pathogenesis Multi-Platform Omics Analysis
Multi-platform omics analyses of peripheral blood mononuclear cells and plasma derived from human patients infected with Ebola virus.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000080129 | MassIVE
ProteomicsHuman Calu-3 cell proteome response to a wild type infectious clone of H7N9 and mutant H7N9 viruses
Proteomics data from Calu-3 cell culture; Treated with wild-type and mutant H7N9 and mockulum; Time points 0, 3, 7, 12, 18 & 24 h; 5 biological replicates
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Calu-3 Cells 
2015-06-17 | MSV000079164 | MassIVE
ProteomicsHuman Calu-3 cell proteome response to Middle Eastern Respiratory Syndrome (icMERS) coronavirus
Proteomics data from Calu-3 cell culture; Treated with wild-type MERS-CoV, MERS-CoV mutants and mockulum; 5 biological replicates
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Middle East Respiratory Syndrome-related Coronavirus (ncbitaxon:1335626) 
2016-08-04 | MSV000080025 | MassIVE
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