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TranscriptomicsSalmon Spawning Migration: Metabolic Shifts and Environmental Triggers
A large-scale functional genomics study revealed shifting energy generating processes in white muscle during the final 1,300 km migration of wild sockeye salmon to their spawning grounds in the Fraser River, British Columbia. In 2006, Lower Adams stock sockeye salmon ceased feeding after passing th...
ORGANISM(S): Oncorhynchus nerka 
2010-05-15 | E-GEOD-13657 | biostudies-arrayexpress
UnknownDevelopment of a qualitative real-time RT-PCR assay for the detection of SARS-CoV-2: a guide and case study in setting up an emergency-use, laboratory-developed molecular microbiological assay.
Not available
S-EPMC8311084 | biostudies-literature
TranscriptomicsGene expression profiling of metastatic lung cancer cell lines
During malignant disease progression, the extracellular matrix (ECM) of epithelial tumors accumulates inter-molecular cross-links between collagen strands; these cross-links enhance ECM stiffness and trigger tumor cell invasion and dissemination, but the mechanisms that regulate intra-tumoral collag...
ORGANISM(S): Mus musculus 
2015-03-12 | E-GEOD-49315 | biostudies-arrayexpress
UnknownDrosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
Not available
S-EPMC4426361 | biostudies-literature
GenomicsHes6 expression is controlled by c-Myc and the AR to promote E2F1 activity and poor outcome in castrate-resistant prostate cancer (E2F1 ChIP-seq)
Hes6 is a transcription co-factor that is associated with stem cell characteristics in neural tissue, but its role in cancer remains uncertain. Here we show that Hes6 is controlled by c-Myc and the AR and can drive castration resistance in xenografts of the androgen-dependent LNCaP prostate cancer c...
ORGANISM(S): Homo sapiens 
2014-04-17 | E-GEOD-36614 | biostudies-arrayexpress
UnknownLysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma.
Not available
S-EPMC4362236 | biostudies-literature
UnknownPragmatic randomized trial evaluating pre-operative aqueous antiseptic skin solution in open fractures (Aqueous-PREP): the feasibility of a cluster randomized crossover study.
Not available
S-EPMC7919062 | biostudies-literature
GenomicsHes6 expression is controlled by c-Myc and the AR to promote E2F1 activity and poor outcome in castrate-resistant prostate cancer (cMyc ChIP-seq)
Hes6 is a transcription co-factor that is associated with stem cell characteristics in neural tissue, but its role in cancer remains uncertain. Here we show that Hes6 is controlled by c-Myc and the AR and can drive castration resistance in xenografts of the androgen-dependent LNCaP prostate cancer c...
ORGANISM(S): Homo sapiens 
2014-04-17 | E-GEOD-37617 | biostudies-arrayexpress
UnknownA pragmatic randomized trial evaluating pre-operative aqueous antiseptic skin solutions in open fractures (Aqueous-PREP): statistical analysis plan.
Not available
S-EPMC9465853 | biostudies-literature
GenomicsHes6 drives a critical AR transcriptional program to induce castration resistant prostate cancer through activation of an E2F1-mediated cell cycle network
Castrate-resistant prostate cancer (CRPC) is poorly characterized and heterogeneous and while the androgen receptor (AR) is of singular importance, other factors such as c-Myc and the E2F family also play a role in later stage disease. Here we show that Hes6 is up-regulated in aggressive human prost...
ORGANISM(S): Homo sapiens 
2014-04-17 | E-GEOD-49832 | biostudies-arrayexpress
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