Sort   by:  
 Page size 
TranscriptomicsExpression data from Control, AKT and RAS transduced cells
Mutations in both RAS and the PTEN/PIK3CA/AKT signaling module are found in the same human tumors. PIK3CA and AKT are downstream effectors of RAS, and the selective advantage conferred by mutation of two genes in the same pathway is unclear. Based on a comparative molecular analysis, we show that ac...
ORGANISM(S): Homo sapiens 
2013-03-19 | E-GEOD-45276 | biostudies-arrayexpress
GenomicsMouse ES cells expressing catalytically inactive Ring1B display impaired Ring1B and H3K27me3 deposition.
ChIP-seq for H3K27me3 and Ring1B was performed in WT mESCs and mESCs containing catalytically inactive Ring1B (I53A mutant). Cells expressing catalytically inactive Ring1B maintain the spatial distribution of Ring1B and H3K27me3 but at reduced levels. These findings support the notion that PRC2 recr...
ORGANISM(S): Mus musculus 
2015-09-20 | E-GEOD-69955 | biostudies-arrayexpress
TranscriptomicsGene expression of a variety of Huh-7 derived hepatoma cells and their susceptibility to infection by JHF1 HCV in the HCV cell culture system.
Hepatitis C virus (HCV) is a global problem. To better understand HCV infection researchers employ in vitro HCV cell-culture (HCVcc) systems that use Huh-7 derived hepatoma cells that are particularly permissive to HCV infection. A variety of hyper-permissive cells have been subcloned for this purpo...
ORGANISM(S): Homo sapiens 
2011-06-11 | E-GEOD-29889 | biostudies-arrayexpress
Unknownd-Cycloserine enhances durability of social skills training in autism spectrum disorder.
Not available
S-EPMC5264460 | biostudies-literature
MetabolomicsHuman Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...
2019-07-04 | MTBLS726 | MetaboLights
UnknownMental health in UK Biobank: development, implementation and results from an online questionnaire completed by 157 366 participants.
Not available
S-EPMC6020276 | biostudies-literature
GenomicsHigh-throughput semi-quantitative analysis of insertional mutations in heterogeneous tumors
Exploiting the full potential of insertional mutagenesis screens with retroviruses and transposons requires methods for distinguishing clonal from subclonal insertion events within heterogeneous tumor cell populations. Current protocols, based on ligation mediated PCR, depend on endonuclease based f...
ORGANISM(S): Mus musculus 
2011-08-11 | E-GEOD-22657 | biostudies-arrayexpress
TranscriptomicsProfiling of Dolphin Skin Cells
3 technical replicates from Wild Dolphin PBL Keywords: Immune and stress response analysis Analyzed 3 arrays with a 3 replicate series.
ORGANISM(S): Tursiops truncatus 
2006-04-01 | E-GEOD-4580 | biostudies-arrayexpress
UnknownThe bone marrow microenvironment at single-cell resolution.
Not available
S-EPMC6607432 | biostudies-literature
TranscriptomicsComparison of mRNA expression in circulating T-cells from patients with severe asthma
Comparison of mRNA expression showed widespread changes in the circulating CD8+ but not CD4+ T-cells from patients with severe asthma. No changes were observed in the CD4+ and CD8+ T-cells in non-severe asthmatics versus healthy controls. Bioinformatics analysis showed that the changes in CD8+ T-cel...
ORGANISM(S): Homo sapiens 
2011-08-31 | E-GEOD-31773 | biostudies-arrayexpress
Sort   by:  
 Page size