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MetabolomicsMetabolomics-Based Analysis of Adaptive Mechanism of Eleutheronema tetradactylum to Low-Temperature Stress

Temperature is a critical environmental factor influencing fish physiology. Eleutheronema tetradactylum is an economically important warm-water species, but its response to long-term cold stress remains unclear. In this study, we exposed juvenile fish to 18 °C for 7 and 14 days and investigated h...

2026-09-08 | MTBLS15459 | MetaboLights
MetabolomicsStress-induced enrichment of Pseudomonas sp. stimulates the adaptive response of Auxenochlorella pyrenoidosa and antibiotic-resistant proliferation

The phycosphere is an important ecological niche for bacteria and antibiotic resistance genes (ARGs). However, whether and how the interaction between microalgae and bacteria changed, and its further effect on the transmission of ARGs under pollutant stress remains enigmatic. Here, Auxenochlorell...

2025-09-26 | MTBLS11371 | MetaboLights
MetabolomicsRevealing the Adaptive Metabolic Differences of Different Sheep Breeds in Plateau Areas Based on the Gut-Heart Axis

Gut microbiota plays a significant role in maintaining the homeostasis of the gut internal environment, and the volatile fatty acids (VFAs) produced by it are the main source of energy utilization for the host. The heart, as a key metabolic organ of the body, its energy metabolism efficiency dire...

2025-09-11 | MTBLS12982 | MetaboLights
TranscriptomicsComparative evaluation of Oxford Nanopore Technologies’ adaptive sampling and the Twist long-read PGx panel for pharmacogenomic profiling
We used targeted long-read Oxford Nanopore Technologies sequencing enriching for a panel of 1036 pharmacogenes extracted from the PharmGKB database. The enrichment was performed using ONT's adaptive sampling feature, enabling in silico enrichment without physically capturing the fragments of interes...
ORGANISM(S): Homo sapiens 
2025-12-30 | E-MTAB-15248 | biostudies-arrayexpress
ProteomicsQuantitative proteomics reveals the antibiotics adaptive mechanism of Aeromonas hydrophila in kanamycin stress
Aeromonas hydrophila is a widespread opportunistic pathogen of aquatic fishes in freshwater habitats. The current emergence of antimicrobial-resistant A. hydrophila has been reported in the world while the bacterial antibiotics adaptive mechanism is still largely known. In this study, using quantita...
ORGANISM(S): Aeromonas Hydrophila Subsp. Hydrophila Al09-71 
2022-04-25 | PXD031300 |
ProteomicsQuantitative proteomic analysis reveals the metabolic characteristics and adaptive mechanism of Cupriavidus oxalaticus in the process of simultaneous nitrogen and phenol removal
The ability of Cupriavidus oxalaticus T2 to simultaneously remove nitrogen and phenol has been confirmed. To explore the metabolic characteristics and adaptive mechanism of Cupriavidus oxalaticus T2 during the simultaneous removal of phenol and nitrogen process, the differences in proteomic profile ...
ORGANISM(S): Cupriavidus Oxalaticus Nbrc 13593 
2021-07-20 | PXD027449 |
GenomicsBRD2 upregulation as a pan-cancer adaptive resistance mechanism to BET inhibition [RNA-seq]
BRD2 upregulation as a pan-cancer adaptive resistance mechanism to BET inhibition [RNA-seq]
PRJNA1315143 | ENA
GenomicsBRD2 upregulation as a pan-cancer adaptive resistance mechanism to BET inhibition [ChIP-seq]
BRD2 upregulation as a pan-cancer adaptive resistance mechanism to BET inhibition [ChIP-seq]
PRJNA1315144 | ENA
GenomicsExperimental evolution identifies adaptive aneuploidy as a mechanism of fluconazole resistance in Candida auris
Experimental evolution identifies adaptive aneuploidy as a mechanism of fluconazole resistance in Candida auris
PRJNA563631 | ENA
GenomicsAdaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition
Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition
PRJNA554692 | ENA
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