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Mammary ductal epithelium controls cold-induced adipocyte thermogenic program
Obesity has become a major public health crisis given its rampant growth and association with an increased risk for cancer. Cancer patients who present with obesity tend to have increased tumor burden and decreased T-cell function, yet it remains unclear how obesity compromises T-cell mediated immun...
ORGANISM(S): Mus musculus 
2026-06-20 | GSE335537 | GEO
We investigated the possibility that adipocyte mediated stress protection is accompanied by activation of a selective mRNA translation analogous to stress induced translational arrest. Nalm-6 cells were subjected at +24 and +48h under 3T3-L1 adipocyte co-culture to Pulsed Stable Isotope Chromatograp...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD019369 | Pride
Sympathetic activation during cold exposure increases adipocyte thermogenesis via the expression of mitochondrial protein uncoupling protein 1 (UCP1)1. The propensity of adipocytes to express UCP1 is under a critical influence of the adipose microenvironment and varies between sexes and among variou...
ORGANISM(S): Mus musculus 
2023-05-01 | GSE231394 | GEO
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