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MetabolomicsSalmonella Modulates Metabolism during Growth under Conditions that Induce Expression of Virulence Genes
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a facultative pathogen that uses complex mechanisms to invade and proliferate within mammalian host cells. To investigate possible contributions of metabolic processes to virulence in S. Typhimurium grown under conditions known to induce ex...
2013-05-02 | MTBLS35 | MetaboLights
UnknownPhase II study of the safety and antitumor activity of the hypoxia-activated prodrug TH-302 in combination with doxorubicin in patients with advanced soft tissue sarcoma.
Not available
S-EPMC4588714 | biostudies-literature
MetabolomicsA Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection
The potential for commensal microorganisms indigenous to a host (the microbiome or microbiota) to alter infection outcome by influencing host-pathogen interplay is largely unknown. We used a multi-omics systems approach, incorporating proteomics, metabolomics, glycomics, and metagenomics, to explore...
2014-06-24 | MTBLS96 | MetaboLights
MetabolomicsModel-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation
Macrophages are central players in immune response, manifesting divergent phenotypes to control inflammation and innate immunity through release of cytokines and other signaling factors. Recently, the focus on metabolism has been reemphasized as critical signaling and regulatory pathways of human pa...
2012-09-05 | MTBLS23 | MetaboLights
TranscriptomicsModel-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation
We used genome-scale modeling and multi-omics (transcriptomics, proteomics, and metabolomics) analysis to assess metabolic features that are critical for macrophage activation. We constructed a genome-scale metabolic network for the RAW 264.7 cell line to determine metabolic modulators of activation...
ORGANISM(S): Mus musculus 
2012-08-02 | E-GEOD-39785 | biostudies-arrayexpress
TranscriptomicsLPS treatment of RAW2647 macrophages
Macrophages are central players in the immune response and manifest divergent phenotypes to control inflammation and innate immunity. Signaling factors are traditionally recognized as the stimuli governing macrophage functions. In recent years, metabolism’s importance has been reemphasized as critic...
ORGANISM(S): Mus musculus 
2012-01-24 | E-GEOD-35237 | biostudies-arrayexpress
UnknownAssociation of Baseline Factors With Glycemic Outcomes in GRADE: A Comparative Effectiveness Randomized Clinical Trial.
Not available
S-EPMC10973909 | biostudies-literature
UnknownComprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes.
Not available
S-EPMC11387199 | biostudies-literature
UnknownGenetic association study of childhood aggression across raters, instruments, and age.
Not available
S-EPMC8324785 | biostudies-literature
ProteomicsHUPO Plasma Proteome Project - Advancement of biomarker discovery and validation through the HUPO plasma proteome project
esi-quadrupole tof survey of tryptic peptides from HUPO pooled Human plasma or serum specimen: b1-serum.
ORGANISM(S): Homo sapiens (Human) 
2007-04-23 | PRD000002 | Pride
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