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TranscriptomicsGene expression profiling in human ADPKD cell lines
Changes in gene expression levels were identified by microarray. Samples were human kidney epithelial cell lines derived from patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) and unaffected controls. Autosomal Dominant Polycystic Kidney Disease (ADPKD), the most common inherited k...
ORGANISM(S): Homo sapiens 
2017-07-05 | E-MTAB-4188 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling in human ADPKD cell lines
Changes in microRNA expression levels were identified by microarray. Samples were human kidney epithelial cell lines derived from patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) and unaffected controls. Autosomal Dominant Polycystic Kidney Disease (ADPKD), the most common inherit...
ORGANISM(S): Homo sapiens 
2017-07-05 | E-MTAB-4189 | biostudies-arrayexpress
TranscriptomicsIdentification of a novel risk factor for intracranial aneurysms in ADPKD using iPSC models [Agilent]
Cardiovascular complications are the leading cause of death in autosomal dominant polycystic kidney disease (ADPKD), and intracranial aneurysm (ICA) causing subarachnoid hemorrhage is among the most serious complications. The diagnostic and therapeutic strategies for ICAs in ADPKD have not been full...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-74451 | biostudies-arrayexpress
TranscriptomicsIdentification of a novel risk factor for intracranial aneurysms in ADPKD using iPSC models [Affymetrix]
Cardiovascular complications are the leading cause of death in autosomal dominant polycystic kidney disease (ADPKD), and intracranial aneurysm (ICA) causing subarachnoid hemorrhage is among the most serious complications. The diagnostic and therapeutic strategies for ICAs in ADPKD have not been full...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-74452 | biostudies-arrayexpress
TranscriptomicsExpression data from renal cysts of autosomal dominant polycystic kidney disease (ADPKD) patients
To elucidate the molecular pathways that modulate renal cyst growth in autosomal dominant polycystic kidney disease (ADPKD) Keywords: Disease state analysis We performed global gene profiling on renal cysts of different size (small cysts: less than 1 ml, n=5; medium cysts: between 10-25 ml, n=5; lar...
ORGANISM(S): Homo sapiens 
2009-08-14 | E-GEOD-7869 | biostudies-arrayexpress
MetabolomicsMetabolomic Profiling of Renal Cyst Fluid in Advanced ADPKD: Insights from Dialysis and Transplantation Cohorts

Background: Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder characterized by progressive renal cyst formation, often leading to end-stage kidney disease (ESKD). While urinary metabolomics in ADPKD has been extensively studied, the composition of renal cyst fluid, par...

2025-07-07 | MTBLS12372 | MetaboLights
UnknownThe BC ADPKD Network: A Comprehensive Provincial Approach to Support Specialized and Locally Delivered Multidisciplinary ADPKD Care.
Not available
S-EPMC8330454 | biostudies-literature
TranscriptomicsIdentification of a novel risk factor for intracranial aneurysms in ADPKD using iPSC models
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-74453 | biostudies-arrayexpress
TranscriptomicsGene expression in early phases of Autosomal Dominant Polycystic Kidney Disease
Little is known about the genes involved in the initial cyst formation and disease progression in autosomal dominant polycystic kidney disease (ADPKD). To uncover the genetic determinants and molecular mechanisms of ADPKD, we analyzed 4-point time-series DNA microarrays from Pkd1L3/L3 mice to genera...
ORGANISM(S): Mus musculus 
2008-12-28 | E-GEOD-13452 | biostudies-arrayexpress
TranscriptomicsEpigenetic silencing of PKD1 in autosomal dominant polycystic kidney disease
ADPKD (Autosomal dominant polycystic kidney disease) is the most common inherited disorders and is characterized by growth of numerous cysts filled with fluid in the kidneys. Ultimately, it leads to kidney failure. The mutations of PKD1 and PKD2 account for approximately 85 and 15 percent of ADPKD, ...
ORGANISM(S): Homo sapiens 
2012-02-16 | E-GEOD-35831 | biostudies-arrayexpress
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