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ProteomicsProteome wide screening for ubiquitination, ISGylation and NEDDylation sites in wildtype and ISG15 knockout mouse hearts after transverse aortic constriction
Hearts(left ventricles) were harvested from control wildtype and ISG15 knockout mice and wildtype and ISG15 knockout mice 4 weeks after pressure overload induced by transverse aortic constriction. Nano LC-MS/MS analysis was performedon left ventricle tissue following protein extraction, trypsin dige...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD032267 | Pride
Isgylation Mouse K-e-gg motif Heart Ubiquitination Tac 
TranscriptomicsGenome wide mapping of H3K27me3 in differentiated mouse podocytes
We explored H3K27me3 binding sites in the genome of differentiated, conditionally immortalized mouse podocytes. Cells were allowed to differentiate for 14 days, following thermoshifting, before treatment with either vehicle (DMSO) or the S-adenosylhomocysteine hydrolase inhibitor 3-deazaneplanocin ...
ORGANISM(S): Mus musculus 
2015-12-09 | E-GEOD-69610 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of high glucose and DZNep (EZH2 inhibitor) induced gene expression by mouse podocytes
Analysis of DZNep-induced gene expression changes in cultured podocytes. The hypothesis tested in the present study was that DZnep ultimately augments Txnip expression, increasing oxidative stress in podocytes. These results provide important information on the response of podocytes to histone methy...
ORGANISM(S): Mus musculus 
2015-12-09 | E-GEOD-60038 | biostudies-arrayexpress
UnknownBrentuximab vedotin in the front-line treatment of patients with CD30+ peripheral T-cell lymphomas: results of a phase I study.
Not available
S-EPMC4171358 | biostudies-literature
GenomicsPrognostic relevance of microenvironmental factors CD163 and CD8 combined with EZH2 and chromosome 18 gain in a validation cohort of follicular lymphoma patients of the Lunenburg Lymphoma Biomarker Consortium
Background: In follicular lymphoma (FL), studies addressing the prognostic value of microenvironment-related immunohistochemical (IHC) markers and tumor cell-related genetic markers have yielded conflicting results, precluding implementation in practice. Therefore, the Lunenburg Lymphoma Biomarker C...
EGAS00001002049 | EGA
Genomicsena-DATASET-VUMC-CCA-12-10-2016-16:43:39:044-188 - samples
Background: In follicular lymphoma (FL), studies addressing the prognostic value of microenvironment-related immunohistochemical (IHC) markers and tumor cell-related genetic markers have yielded conflicting results, precluding implementation in practice. Therefore, the Lunenburg Lymphoma Biomarker C...
EGAD00001002738 | EGA
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