Proteome wide screening for ubiquitination, ISGylation and NEDDylation sites in wildtype and ISG15 knockout mouse hearts after transverse aortic constriction

ABSTRACT: Hearts(left ventricles) were harvested from control wildtype and ISG15 knockout mice and wildtype and ISG15 knockout mice 4 weeks after pressure overload induced by transverse aortic constriction. Nano LC-MS/MS analysis was performedon left ventricle tissue following protein extraction, trypsin digestion, peptide desalting, anti K-e-GG enrichment.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Heart, Ventricular Cardiac Muscle Cell, T Cell, Endothelial Cell, Fibroblast, Macrophage

DISEASE(S): Systolic Heart Failure,Heart Failure

SUBMITTER: Andrew Advani  

LAB HEAD: Andrew Advani

PROVIDER: PXD032267 | Pride | 2023-05-10

REPOSITORIES: Pride