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In this study, the expression profiles of secreted proteins from amniotic mesenchymal stem cells (AMSCs) and amniotic epithelial cells (AECs) were comprehensively analyzed utilizing mass spectrometry-based proteomics.
ORGANISM(S): Homo sapiens (Human) 
2024-11-18 | PXD057076 | Pride
In-vivo inhibition of Fgfr2b signalling in FACS-isolated AECs from embryonic mouse lungs from E16.5 to E18.5
DNA methylation profiling of airway epithelial cells (AECs) and peripheral blood mononuclear cells (PBMCs) from normal, atopic and asthmatic subjects. The Illumina GoldenGate Methylation Cancer Panel I was used to obtain DNA methylation profiles across approximately 1505 CpGs in AECs and PBMCs. Samp...
ORGANISM(S): Homo sapiens 
Rationale: Mast cells (MCs) within the airway epithelium in asthma are closely related to airway dysfunction, but crosstalk between airway epithelial cells (AECs) and MCs in asthma remains incompletely understood. Human rhinovirus (HRV) infections are key triggers for asthma progression and AECs fro...
ORGANISM(S): Homo sapiens 
2022-06-22 | GSE206680 | GEO
Trisomy 21 (TS21), commonly known as Down syndrome (DS), increases mortality risk due to respiratory syncytial virus (RSV) in children by nearly 9-fold. Interferon (IFN)-mediated JAK/STAT antiviral signaling is altered in DS given that four IFN receptor genes reside on chromosome 21. This study unve...
ORGANISM(S): Homo sapiens 
2025-12-12 | GSE271245 | GEO
Airway epithelial cells are crucial for mucosal and adaptive immunity as they produce mucins that trap and clear inhaled particulates by mucociliary activity, and also secrete diverse inflammatory mediators. But whether these cells respond in a memory-dependent manner to a secondary exposure is poor...
ORGANISM(S): Homo sapiens 
2020-12-07 | GSE139370 | GEO
We applied next-generation sequencing to investigate the gene expression profiles in mouse alveolar epithelial cells (AECs). We identified a number of differentially regulated genes in the AECs of mice with bleomycin induced pulmonary fibrosis and LPS induced acute lung injury.
ORGANISM(S): Mus musculus 
2018-02-01 | GSE109913 | GEO
The airway epithelium forms the interface between the inhaled environment and the lung. The airway epithelium is dysfunctional in asthma and epigenetic mechanisms are considered a contributory factor. We hypothesised that the DNA methylation profiles of cultured primary airway epithelial cells (AECs...
ORGANISM(S): Homo sapiens 
2019-10-31 | GSE137716 | GEO
Airway epithelial cells (AEC) are critical components of the inflammatory and immune response during exposure to pathogens. AECs in monolayer culture and differentiated epithelial cells in air-liquid interface (ALI) represent two distinct and commonly used in vitro models, yet differences in their r...
ORGANISM(S): Homo sapiens 
2014-12-01 | GSE55458 | GEO
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