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ProteomicsLIS1 RNA binding orchestartes the mechanosensitive properties of embryonic stem cells in AGO2 dependent and independent ways.
LIS1 immunoprecipitation in nuclear and cytoplasmic fractions of LIS1 Floxed/-, OE and WT embryonic stem cells. To identify AGO2 dependent and independent interactions LIS1 was immunoprecipitated in AGO1-4 knockout and doxycycline induced AGO2 mouse embryonic stem cells.
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD033150 | Pride
Oe Dox.ago2 Ago1-4 ko Nuclear and cytoplasmic fractions Flox/- Wt Mouse embyonic stem cells Lis1 ip 
TranscriptomicsEndothelial AGO1 Deficiency Reduces Breast Cancer Burden in Mice
Endothelial cells are crucial in cancer development and progression, in part through tumor angiogenesis and immune modulation. As a key component of RNA-induced silencing complex, Argonaute 1 (AGO1) protein has been shown to regulate tumor biology. However, its role in ECs within the tumor microenvi...
ORGANISM(S): Mus musculus 
2026-06-18 | GSE310768 | GEO
TranscriptomicsMolecular and Functional Characterization of the role of RNA silencing components in Cryptococcus neoformans [RNAi_Serotype D]
The RNA interference (RNAi) mediated by homology-dependent degradation of the target mRNA with small RNA molecules plays a key role in controlling transcription and translation processes in a number of eukaryotic organisms. The RNAi machinery is also evolutionarily conserved in a wide variety of fun...
ORGANISM(S): Cryptococcus neoformans var. neoformans JEC21 
2010-05-01 | E-GEOD-21177 | biostudies-arrayexpress
ProteomicsProSeAM SILAC MS screening for METTL9 substrates
Click chemistry based substrates screening for METTL9 in Mettl9 KO MEF cells.
ORGANISM(S): Mus Musculus (mouse) 
2020-11-19 | PXD016823 | JPOST Repository
GenomicsEndothelial AGO1 Deficiency Reduces Breast Cancer Burden in Mice
Endothelial AGO1 Deficiency Reduces Breast Cancer Burden in Mice
PRJNA1367051 | ENA
TranscriptomicsHepatitis C virus functionally sequesters miR-122 [miR-122 KO vs Control CLIP]
Hepatitis C virus uniquely requires the liver specific microRNA-122 for replication, yet global effects on endogenous miRNA targets during infection are unexplored. Here, high-throughput sequencing and crosslinking immunoprecipitation (HITS-CLIP) experiments of human Argonaute (Ago) during HCV infec...
ORGANISM(S): Homo sapiens 
2015-01-06 | E-GEOD-64679 | biostudies-arrayexpress
TranscriptomicsMolecular and Functional Characterization of the role of RNA silencing components in Cryptococcus neoformans [RNAi_Serotype A]
The RNA interference (RNAi) mediated by homology-dependent degradation of the target mRNA with small RNA molecules plays a key role in controlling transcription and translation processes in a number of eukaryotic organisms. The RNAi machinery is also evolutionarily conserved in a wide variety of fun...
ORGANISM(S): Cryptococcus neoformans var. grubii H99 
2010-05-01 | E-GEOD-21176 | biostudies-arrayexpress
UnknownSuppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis.
Not available
S-EPMC5791084 | biostudies-literature
GenomicsArgonaute3-SF3B3 complex controls pre-mRNA splicing to restrain Type-2 immunity [RNA-seq: cultured cells]
Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain Type-2 immunity [RNA-seq: cultured cells]
PRJNA1019659 | ENA
GenomicsArgonaute3-SF3B3 complex controls pre-mRNA splicing to restrain Type-2 immunity [miRNA-seq]
Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain Type-2 immunity [miRNA-seq]
PRJNA1020567 | ENA
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