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MetabolomicsMetabolomics Analysis Identifies Glutamic acid and Cystine imbalances in COVID-19 Patients Without Comorbid Conditions. Implications on Redox Homeostasis and COVID-19 Pathophysiology

It is well known that the presence of comorbidities and age-related health issues may hide biochemical and metabolic features triggered by SARS-CoV-2 infection and other diseases associated to hypoxia, as they are by themselves chronic inflammatory conditions that may potentially disturb metaboli...

2024-08-26 | MTBLS5011 | MetaboLights
GenomicsNuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer
Sporadic colorectal cancer (CRC) insurgence and progression depend on the activation of Wnt/?-catenin signaling. Dickkopf (DKK)-1 is an extracellular inhibitor of Wnt/?-catenin signaling that also has undefined ?-catenin-independent actions. Here we report for the first time that a proportion of DKK...
ORGANISM(S): Homo sapiens 
2015-05-13 | E-GEOD-31170 | biostudies-arrayexpress
UnknownThioredoxin and glutaredoxin regulate metabolism through different multiplex thiol switches.
Not available
S-EPMC6327914 | biostudies-literature
GenomicsGenome-Wide Association Study of Hypertriglyceridemia in Mexicans

Coronary artery disease (CAD) is the number one cause of death and mortality world-wide. High levels of serum triglycerides (TGs) and low levels of serum high-density lipoprotein cholesterol (HDL-C) are major risk factors for CAD. Previous epidemiological studies have shown that these two lipid d...

phs000618.v1.p1 | EGA
UnknownUniversal mental health screening with a focus on suicidal behaviour using smartphones in a Mexican rural community: protocol for the SMART-SCREEN population-based survey.
Not available
S-EPMC7371217 | biostudies-literature
UnknownTwo novel variants in DYRK1B causative of AOMS3: expanding the clinical spectrum.
Not available
S-EPMC8247206 | biostudies-literature
TranscriptomicsGenome-wide mRNA expression profiles induced by infection with the pandemic and seasonal influenza A viruses in macrophages
Infection with pandemic A/H1N1 influenza virus induces high levels of circulating and lung pro-inflammatory cytokines and chemokines in experimental models and humans. These inflammatory mediators contribute to poor clinical outcomes of this infection. To compare the regulation of inflammatory respo...
ORGANISM(S): Homo sapiens 
2012-06-09 | E-GEOD-36012 | biostudies-arrayexpress
UnknownPathogenetic and Prognostic Implications of Increased Mitochondrial Content in Multiple Myeloma.
Not available
S-EPMC8268477 | biostudies-literature
UnknownClinical characterization of data-driven diabetes subgroups in Mexicans using a reproducible machine learning approach.
Not available
S-EPMC7380860 | biostudies-literature
UnknownPredictors of failure with high-flow nasal oxygen therapy in COVID-19 patients with acute respiratory failure: a multicenter observational study.
Not available
S-EPMC7934982 | biostudies-literature
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