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pride
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Mass Spectrometry
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2020
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2019
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Department of Chemistry, King's College London
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Lecturer in Chemical Systems Biology Department of Chemistry King's College London
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Investigating the dynamics of the SecA–SecYEG complex dynamic by HDX-MS
We employ hydrogen-deuterium exchange mass spectrometry (HDX-MS) to investigate the conformational dynamics required to facilitate based Brownian ratchet mechanism for protein secretion (by the SecA-SecYEG complex).
ORGANISM(S):
Escherichia coli
2019-07-16
|
PXD013594
|
Pride
Seca–secyeg
Hdx-ms
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HDX-MS reveals the perturbed structural dynamics underlie inhibition and altered specificity of the multidrug efflux pump AcrB
Perturbed structural dynamics underlie inhibition and altered specificity of the multidrug efflux pump AcrB
ORGANISM(S):
Escherichia coli
2020-10-07
|
PXD019047
|
Pride
Acrb
Hdx-ms
Membrane proteins
Multi-drug efflux pumps
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