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MetabolomicsHorizontal Transfer of Bacteriocin Biosynthesis Genes Requires Metabolic Adaptation To Improve Compound Production and Cellular Fitness

Biosynthetic gene clusters (BGCs) encoding the production of bacteriocins are widespread among bacterial isolates and are important genetic determinants of competitive fitness within a given habitat. Staphylococci produce a tremendous diversity of compounds, and the corresponding BGCs are frequen...

2022-11-09 | MTBLS5196 | MetaboLights
MetabolomicsTargeted metabolomic analysis in hepatic extracts, serum, and urine of female mice gavaged with TCDD every 4 days for 28 days
TCDD is an environmental contaminant that elicits a number of hepatic effects including fat accumulation, inflammation, and fibrosis that can progress to hepatocellular carcinoma. RNA-Seq and targeted metabolomics were integrated with complementary dioxin response element (DRE) location and aryl hyd...
2017-02-02 | MTBLS225 | MetaboLights
ProteomicsSPARCS enables scalable recovery of complex image-based phenotypes for genetic screening
Forward genetic screening links genotype to phenotype by introducing random genetic perturbations and identifying phenotype-altering mutations. Although genome-scale screens are routine for simple phenotypes in cultured cells, extending them to complex image-based phenotypes remains challenging. Her...
ORGANISM(S): Homo sapiens (Human) 
2026-10-06 | PXD082653 | Pride
Sting Cell culture 
UnknownVirulence traits and novel drug delivery strategies for mucormycosis post-COVID-19: a comprehensive review.
Not available
S-EPMC10561264 | biostudies-literature
UnknownBeauty Inside Out: Examining Beauty Product Use Among Diverse Women and Femme-Identifying Individuals in Northern Manhattan and South Bronx Through an Environmental Justice Framework.
Not available
S-EPMC10704575 | biostudies-literature
ProteomicsDiscovery and validation of serum glycoprotein biomarker panel for detection of high grade serous ovarian cancer
We aimed to discover and validate a panel of serum biomarkers for high grade serous ovarian cancer (HGSOC) using our lectin-magnetic bead array-coupled proteomics platform. Serum from age-matched women with HGSOC, benign tumours or healthy controls were analysed in discovery (UKCTOCS, n=30 and UKOPS...
ORGANISM(S): Homo Sapiens 
2024-08-06 | PXD033108 | panorama
ProteomicsTargeted and non-targeted mass spectrometry to explore the chemical diversity of the genus Gambierdiscus in the Atlantic Ocean
The 15 strains of Gambierdiscus were cultivated in four separate laboratories. Each laboratory grew their available strains (see sample metadata) in addition to the G. australes strain AUS S080911_1 isolated from Pacific Ocean. Irradiance (70-100 umol photons m-2 s-1) and light/dark cycle (12h:12h)...
ORGANISM(S): Gambierdiscus Silvae (ncbitaxon:1550089) Gambierdiscus Carolinianus (ncbitaxon:864182) Gambierdiscus Australes (ncbitaxon:439317) Gambierdiscus Belizeanus (ncbitaxon:439316) Gambierdiscus Excentricus (ncbitaxon:986170) Gambierdiscus Caribaeus (ncbitaxon:864185) 
2024-02-26 | MSV000094172 | MassIVE
UnknownTrajectories of resting energy expenditure and performance of predictive equations in children hospitalized with an acute illness and malnutrition: a longitudinal study.
Not available
S-EPMC10864294 | biostudies-literature
UnknownRothmund-Thomson Syndrome: novel pathogenic mutations and frequencies of variants in the RECQL4 and USB1 (C16orf57) gene.
Not available
S-EPMC4867568 | biostudies-literature
UnknownAnalysis of therapy monitoring in the International Congenital Adrenal Hyperplasia Registry.
Not available
S-EPMC9796837 | biostudies-literature
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