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TranscriptomicsTranscription analysis of AI-2 signal add in experiment in Yersinia pestis CO92 at 37M-BM-0C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of autoinducer-2 (AI-2) quorum sensing was investigated by comparing transcript profiles when AI-2 quorum-sensing signal is a...
ORGANISM(S): Yersinia pestis 
2013-09-05 | E-GEOD-22848 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of AI-2 treatment in Yersinia pestis at 30°C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of autoinducer-2 (AI-2) quorum sensing was investigated by comparing transcript profiles when AI-2 quorum-sensing signal is a...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30237 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of three quorum sensing signals add in experiment inYersinia pestis CO92 at 37M-BM-0C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of quorum sensing was investigated by comparing transcript profiles when three quorum-sensing signals are added in. The strai...
ORGANISM(S): Yersinia pestis 
2013-09-05 | E-GEOD-22846 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of luxS-null strain in Yersinia pestis CO92 at 37M-BM-0C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of autoinducer 2 (AI-2) quorum sensing was investigated by comparing transcript profiles when luxS gene was knocked out. The ...
ORGANISM(S): Yersinia pestis 
2013-09-05 | E-GEOD-22849 | biostudies-arrayexpress
TranscriptomicsLuxS/AI-2 quorum sensing microarray comparison in Yersinia pestis at 30°C
The AI-2 quorum-sensing system has been linked to diverse phenotypes and regulatory changes in pathogenic bacteria. In strain CO92, the AI-2 signal is produced in a luxS-dependent manner, reaching maximal levels of 2.5 μM in late logarithmic growth, and both wild type and pigmentation mutant strain...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30108 | biostudies-arrayexpress
ProteomicsDiscovery of a bifunctional PKMYT1-targeting PROTAC empowered by AI-generation
PKMYT1 has recently emerged as a compelling therapeutic target for precision cancer therapy due to its synthetic lethality with oncogenic alterations such as CCNE1 amplification and mutations in FBXW7 and PPP2R1A. Current small molecule PKMYT1 inhibitors face limitations, such as insufficient molecu...
ORGANISM(S): Homo sapiens (Human) 
2025-09-28 | PXD062889 | Pride
Protac Pkmyt1 Synthetic lethality Ai-generation 
ProteomicsMassNet: billion-scale AI-ready mass spectral corpus empowering scalable deep learning in proteomics
Breakthroughs in artificial intelligence (AI) for natural language processing and computer vision have been largely driven by high-quality, large-scale datasets such as OpenWebText and ImageNet. Inspired by this, we present MassNet, a foundational resource for proteomics designed to accelerate deep ...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) Toxoplasma gondii Glycine max Mus musculus (Mouse) Capsicum annuum Acinetobacter baumannii Sus scrofa domesticus (domestic pig) Rhodopseudomonas palustris Homo sapiens (Human) Zea mays (Maize) Streptomyces coelicolor Callithrix jacchus Rattus norvegicus (Rat) Bacillus subtilis Legionella pneumophila Arabidopsis thaliana (Mouse-ear cress) Trypanosoma brucei Staphylococcus epidermidis Gallus gallus (Chicken) Drosophila melanogaster (Fruit fly) Oryza sativa (Rice) Caenorhabditis elegans Bacillus cereus Chlamydomonas reinhardtii Bos taurus (Bovine) Moorella thermoacetica Zymomonas mobilis Oryctolagus cuniculus (Rabbit) Pseudomonas aeruginosa Coffea arabica (Arabian coffee) Canis familiaris (Dog) (Canis lupus familiaris) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) Staphylococcus aureus Equus caballus (Horse) 
2026-10-20 | PXD071590 | Pride
TranscriptomicsTranscriptional analysis of quorum sensing deficient in Yersinia pestis CO92 at 37M-BM-0C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of quorum sensing was investigated by comparing transcript profiles when three quorum-sensing synthase genes are knocked out....
ORGANISM(S): Yersinia pestis 
2013-09-05 | E-GEOD-21911 | biostudies-arrayexpress
UnknownProspective Multi-Site Validation of AI to Detect Tuberculosis and Chest X-Ray Abnormalities.
Not available
S-EPMC11737584 | biostudies-literature
Transcriptomics3 quorum sensing signals add in microarray comparison in Yersinia pestis at 30°C
The quorum-sensing system has been linked to diverse phenotypes and regulatory changes in pathogenic bacteria. In strain CO92, the AI-2 signal is produced in a luxS-dependent manner, reaching maximal levels of 2.5 μM in late logarithmic growth, and both wild type and pigmentation mutant strains mad...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30109 | biostudies-arrayexpress
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