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TranscriptomicsExpression data in the mouse brain following the glucocorticoid receptor overexpression in the forebrain (GRov) during different periods in development
The glucocorticoid receptor overexpression in early life is sufficient to alter gene expression patterns for the rest of the animal's life. Hippocampal dentate gyrus (DG) are more responsive than the nucleus accumbens (NAcc) following the glucocorticoid receptor overexpression in the forebrain. Lase...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-30187 | biostudies-arrayexpress
TranscriptomicsSample Matching by Inferred Agonal Stress in Gene Expression Analyses of the Brain
Gene expression patterns in the brain are strongly influenced by the severity of physiological stress at death. This agonal effect, if not well controlled, can lead to spurious findings in case-control comparisons. While many recent studies match samples by tissue pH and clinically recorded agonal...
ORGANISM(S): Homo sapiens 
2010-10-08 | E-GEOD-6306 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of post-mortem human brain to investigate gender specific gene expression
Gender differences in brain development and in the prevalence of neuropsychiatric disorders such as depression have been reported. Gender differences in human brain might be related to patterns of gene expression. Microarray technology is one useful method for investigation of gene expression in bra...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2164 | biostudies-arrayexpress
TranscriptomicsCircadian patterns of gene expression in the human brain and disruption in major depressive disorder
A cardinal symptom of Major Depressive Disorder (MDD) is the disruption of circadian patterns. Yet, to date, there is no direct evidence of circadian clock dysregulation in the brains of MDD patients. Circadian rhythmicity of gene expression has been observed in animals and peripheral human tissues,...
ORGANISM(S): Homo sapiens 
2013-04-20 | E-GEOD-45642 | biostudies-arrayexpress
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