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TranscriptomicsRelA and RelB-dependent transcriptome analysis in lymphotoxin-ß receptor stimulated mouse embryonic fibroblasts
Background: Lymphotoxin signaling via the lymphotoxin-β receptor (LTβR) has been implicated in several biological processes, ranging from development of secondary lymphoid organs, maintenance of splenic tissue, host defense against pathogens, autoimmunity, and lipid homeostasis. The major transcript...
ORGANISM(S): Mus musculus 
2008-12-17 | E-GEOD-11963 | biostudies-arrayexpress
ProteomicsThe response of B. pumilus cells to glucose starvation
In this study the proteome of soluble intracellular and extracellular samples have been analysed of the gram positive BAcillus pumilus.
ORGANISM(S): Bacillus pumilus 
2018-07-05 | PXD005602 | Pride
Keywords bacillus pumilus/ glucose starvation/ proteome 
ProteomicsAnoxia in Ralstonia eutropha H16
Ralstonia eutropha H16 is a denitrifying microorganism able to use nitrate and nitrite as terminal electron acceptors under oxygen deprivation. To identify proteins showing an altered expression pattern in response to oxygen supply, R. eutropha cells grown aerobically and anaerobically were compared...
ORGANISM(S): Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha) 
2014-09-01 | PXD000888 | Pride
Denitrification Membrane proteins Ralstonia eutropha h16 Anaerobiosis Spectral counting 
ProteomicsChemical proteomic profiling reveals protein interactors of the alarmones diadenosine triphosphate and tetraphosphate
The nucleotides diadenosine triphosphate (Ap3A) and diadenosine tetraphosphate (Ap4A) are formed in prokaryotic and eukaryotic cells. Since their concentrations increase significantly upon cellular stress, they are considered to be alarmones triggering stress adaptive processes. However, their cellu...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2022-02-15 | PXD020740 | Pride
Photo-affinity labeling Proteomics Apna 
TranscriptomicsMolecular anatomy of gene expression responses in stressed hepatocytes
It is well-known that isolation and cultivation of primary hepatocytes causes major gene expression alterations. In the present genome-wide, time resolved study of cultivated human and mouse hepatocytes, we made the observation that expression changes in culture strongly resemble alterations in live...
ORGANISM(S): Mus musculus 
2016-09-28 | E-MTAB-4444 | biostudies-arrayexpress
TranscriptomicsNTRAS hnRNPL RNA sequencing in HUVECs
In the current project with aim to unequivocally characterize a novel splicing-regulatory network that proves to be a central mediator of endothelial barrier function and vascular integrity. At the core of this network is the endothelial enriched lncRNA NTRAS (annotated as RP11-354k1.1) is shown to ...
ORGANISM(S): Homo sapiens 
2022-01-10 | E-MTAB-11311 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling by array of pancreatic ductal adenocarcinoma xenograft models
We generated novel patient derived xenograft (PDX) and cell line -derived xenograft models for pancreatic ductal adenocarcinoma (PDAC) which reflect different molecular subtypes. Pancreatic ductal adenocarcinoma is currently the tumor with the fourth highest mortality rate. Recently, subtypes of PDA...
ORGANISM(S): Homo sapiens 
2016-01-12 | E-MTAB-4029 | biostudies-arrayexpress
UnknownA Protein Quality Control Pathway Regulated by Linear Ubiquitination
Not available
S-SCDT-EMBOJ-2018-100730 | biostudies-other
UnknownThe splicing-regulatory lncRNA NTRAS sustains vascular integrity
Not available
S-SCDT-EMBOR-2021-54157-T | biostudies-other
ModelsSobotta2017 - IL-6-induced JAK1-STAT3-signaling
Here we present a mathematical model of IL-6-induced JAK1-STAT3 signaling that quantitatively links physiological IL-6 concentrations to the dynamics of IL-6-induced signal transduction and expression of target genes in hepatocytes. The mathematical model consists of coupled ordinary differential eq...
2023-07-05 | MODEL2307050001 | BioModels
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