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Alcohol-associated liver disease (ALD) is a growing global health concern, with alcohol-associated hepatitis (AH) leading to the highest morbidity and mortality. Available therapies are limited and often inadequate. Platelets contribute in a variety of ways to the pathogenesis of liver diseases, but...
ORGANISM(S): Homo sapiens (Human) 
2026-06-26 | PXD078511 | Pride
Exome sequencing of Alcohol-associated Hepatitis
Exome sequencing of Alcohol-associated Hepatitis
Platelet-derived S100A9 contributes to Endotheliopathy in Alcohol-Associated Hepatitis
Background & Aims: Alcohol-associated hepatitis (AH) is an acute form of alcohol-related liver disease (ArLD) with high mortality rate. AH is histologically characterised by cellular processes including steatosis, inflammation and cell death. Apoptosis is the most studied form of cell death in AH; h...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD053109 | Pride
Alcohol-associated hepatitis induces hepatocyte senescence which is reduced following disease resolution II
Alcohol-associated hepatitis induces hepatocyte senescence which is reduced following disease resolution I
IL-8+ neutrophils drive inexorable inflammation in severe alcohol-associated hepatitis [scRNA-seq]
Platelet-derived S100A9 contributes to Endotheliopathy in Alcohol-Associated Hepatitis [PBS and Aspirin]
Transcriptomics of liver and PBMCs in alcohol-associated liver disease
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