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MetabolomicsImpact of genetic suppression (shRNA) of ALDH1A1 expression in human colon cancer cell line (COLO320)
Not available
ORGANISM(S): Homo sapiens 
ST001093 | MetabolomicsWorkbench
MetabolomicsPharmacological Targeting of ALDH1a2 in Dendritic Cells Enhances Antigen Presentation, T Cell Activation and Anti-tumor immunity
Dendritic cell (DC) vaccines have been proposed as cancer immunotherapies due to their role as crucial antigen-presenting cells that regulate T cell functions. Despite considerable efforts to optimize ex vivo priming of DCs, DC vaccines have rarely been successful, suggesting the presence of unknown...
2025-11-03 | MTBLS10389 | MetaboLights
TranscriptomicssiRNA profiling of human A549 lung cancer cell line following siRNA mediated knock-down of ALDH1A1 and ALDH3A1
Aldehyde dehydrogenase isozymes ALDH1A1 and ALDH3A1 are highly expressed in non small cell cell lung cancer. Neither the mechanism nor the biological significance for such over expression have been studied. We used microarrays to analyze changes in A549 lung cancer cell line in which ALDH activity...
ORGANISM(S): Homo sapiens 
2008-11-13 | E-GEOD-8045 | biostudies-arrayexpress
TranscriptomicsGenomic characterization of ovarian cancer spheroids
Spheroids are 3D multi-cell aggregates formed in non-addherent culture conditions. In ovarian cancer (OC), they serve as a vehicle for cancer cell dissemination in the peritoneal cavity. We investigated genes and networks upregulated in three dimensional (3D) versus two-dimensional (2D) culture cond...
ORGANISM(S): Homo sapiens 
2014-01-03 | E-GEOD-53759 | biostudies-arrayexpress
GenomicsRole of ALDH1A1 in PARPi resistance in ovarian cancer
Role of ALDH1A1 in PARPi resistance in ovarian cancer
PRJNA938376 | ENA
GenomicsGene expression profiling of WT and Aldh1a1 KO mouse lung tissues
Gene expression profiling of WT and Aldh1a1 KO mouse lung tissues
PRJNA1109774 | ENA
GenomicsGene expression profiling of WT and Aldh1a1 KO mouse lung tissues (Part 2)
Gene expression profiling of WT and Aldh1a1 KO mouse lung tissues (Part 2)
PRJNA1259395 | ENA
GenomicsALDH1A1 Promotes Immune Escape of Tumor Cells through ZBTB7B-Glycolysis Pathway
ALDH1A1 Promotes Immune Escape of Tumor Cells through ZBTB7B-Glycolysis Pathway
PRJNA1124139 | ENA
ProteomicsBlood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-ß1 signaling mechanism
Background: Prostate cancer (PCa) is the second most common type of tumor diagnosed in men and the fifth leading cause of cancer-related death in male patients. The response of metastatic disease to standard treatment is heterogeneous. As for now, there is no curative treatment option available for ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD052973 | Pride
Liquid biopsy Aldh1a1 Tgf-ß1 Mmp11 Prostate cancer Metastasis 
ProteomicsActivity-based sensing reveals elevated labile copper promotes liver aging via hepatic ALDH1A1 depletion
Oxidative stress plays a key role in aging and related diseases, including neurodegeneration, cancer, and organ failure. Copper (Cu), a redox-active metal ion, generates reactive oxygen species (ROS), and its dysregulation contributes to aging. Here, we develop activity-based imaging probes for the ...
ORGANISM(S): Mus Musculus (mouse) 
2025-01-16 | PXD059736 | JPOST Repository
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