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We aimed to study the impact of bacteria-derived metabolites in solid organ transplantation. The short-chain fatty acid butyrate was administered using a new drug-delivery method developed by Wang et al. (https://doi.org/10.1038/s41551-022-00972-5). This system is based on a micelle platform that ca...
ORGANISM(S): Mus musculus 
CD4+CD45.1+ TCR75/Rag-/- T cells (TCR75) were adoptively transferred into CD45.2+ B6 or Foxp3-DTR hosts prior to transplantation of a B/c heart (HTx) in the presence or absence (Rej) of anti-CD154 (day 0, day 7, day 14) and DST (day 0) to induce tolerance. A group of tolerant mice were depleted of T...
ORGANISM(S): Mus musculus 
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