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TranscriptomicsTranscription profiling of human adenocarcinoma cell line A549 over-expressing ELMOD2
ELMOD2 cDNA from the IMAGE clone 3897166 was cloned into the pDsRed-Monomer-N1 expression vector. ELMOD2 was overexpressed in the A549(adenomcarcinoma)cell line and cells transfected with empty vector were considered controls. Transcript profiles were compared with the Affymetrix Hgu133plus2 arrays....
ORGANISM(S): Homo sapiens 
2009-12-07 | E-MEXP-1838 | biostudies-arrayexpress
TranscriptomicsNickel-induced contact dermatitis induce changes in human skin transcriptome over 96 hours
We aimed to characterize transcriptomic changes over time (baseline, 2 hours, 48 hours and 96 hours) after nickel-induced contact dermatitis in 6 human probands. As a contrast, 7 patients with SLS-induced irritant contact dermatitis were included. Therefore, the patch tests were applied onto the bac...
ORGANISM(S): Homo sapiens 
2020-05-01 | E-MTAB-8945 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing of lck-GFP transgenic zebrafish
The present study was conducted in the frame of the EU-funded Graphene Flagship project. The aim is to evaluate the impact of graphene oxide (GO) on the (innate) immune system using zebrafish as a model. We previously performed single-cell RNA-sequencing of germ-free zebrafish embryos exposed to GO ...
ORGANISM(S): Danio rerio 
2022-07-23 | E-MTAB-11991 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing of germ-free zebrafish embryos
The present study was conducted in the frame of the EU-funded Graphene Flagship project. We previously evaluated the impact of graphene oxide (GO) on the gut microbiome in adult zebrafish by performing 16S rRNA gene sequencing in wild-type versus AhR-deficient zebrafish. Here, we performed single-c...
ORGANISM(S): Danio rerio 
2022-07-22 | E-MTAB-11984 | biostudies-arrayexpress
TranscriptomicsInhalation of rod-like carbon nanotubes causes unconventional asthma
Exposure to rod-shaped carbon nanotubes reveals novel innate immunity mediated asthma-like inflammation in mice. Inhalation of rCNT elicited a drastic infiltration of eosinophils into the lungs but only minor infiltration of neutrophils and lymphocytes. Transcriptomic study revealed remarkable effec...
ORGANISM(S): Mus musculus 
2014-10-01 | E-GEOD-50176 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human healthy, psoriasis and atopic eczema skin samples
The microRNA expression profile of heathly, psoriasis and atopic eczema skin smaples was compared.
ORGANISM(S): Homo sapiens 
2007-08-16 | E-MEXP-1123 | biostudies-arrayexpress
GenomicsBAMSE Epigene
illumina 450K
EGAD00010001461 | EGA
GenomicsBAMSE (Swedish abbreviation for Children, Allergy, Milieu, Stockholm, Epidemiology)
The BAMSE (Swedish abbreviation for Children, Allergy, Milieu, Stockholm, Epidemiology) study is an ongoing longitudinal, population-based prospective birth cohort including 4,089 children born between 1994 and 1996 in Stockholm, Sweden. The cohort was initially designed to study risk factors for as...
EGAS00001002746 | EGA
GenomicsBAMSE Epigene Data Access Committee
Data Access Committee EGAC00001000786
EGAC00001000786 | EGA
TranscriptomicsMicroarray transcriptome profiling of atopic dermatitis and psoriasis patients compared to healthy volunteers.
Characteization host-microbiome interactions in patients with allergic (model: atopic dermatitis) and autoimmune (model: psoriasis) diseases by integration of microarray transcriptome data with 16S microbial profiling. 6mm punch biopsies were collected from the skin of atopic dermatitis and psorias...
ORGANISM(S): Homo sapiens 
2019-09-11 | E-MTAB-8149 | biostudies-arrayexpress
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