Sort   by:  
 Page size 
TranscriptomicsExpression data from in vitro derived dendritic cells generated in the presence of FLT3-L from wt and miR-142-/- BM cells
2 types of dendritic cells (DCs) can be generated in vitro in the presence of Flt3-L: CD4+ equivalent CD24- DCs and CD8+ equivalent CD24+ DCs. miR-142-/- mice show a severe defect in the generation of CD4+ equivalent CD24- DCs. To understand the underlying mechanism, RNA expression was analyzed by A...
ORGANISM(S): Mus musculus 
2012-11-16 | E-GEOD-42325 | biostudies-arrayexpress
TranscriptomicsAnalysis of wildtype and Csnk2b-deficient Foxp3+ regulatory T cells transcriptomes
The goal of this study was to compare the transcriptional changes evoked by Csnk2b-deficiency in Foxp3+ regulatory T cells Messenger RNA profiles of CD4+Foxp3+ regulatory T cells isolated from 8 week old wild type (WT) and Csnk2b-deficient mice were generated by deep sequencing in duplicate, using I...
ORGANISM(S): Mus musculus 
2015-01-13 | E-GEOD-63961 | biostudies-arrayexpress
TranscriptomicsThe lifespan and kinetics of human Dendritic Cell subsets and their precursors in health and inflammation
To probe the phenotype of the cDC compartment during pathology, we developed a simplified human experimental skin blister model to sample infiltrating cells in order to examine the function and kinetics of DC populations in response to a bacterial insult in healthy individuals. ASDC were recruited t...
ORGANISM(S): Homo sapiens 
2024-09-24 | E-MTAB-14451 | biostudies-arrayexpress
TranscriptomicsInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
B cells from anonymous adenoid donors were isolated and sorted for naïve B cells, which were subsequently infected with a reference EBV strain (2089_B95-8) using a defined multiplicity of infection. Infection of resting B cells with EBV induces their activation, their proliferation, and subsequent i...
ORGANISM(S): Homo sapiens 
2019-07-01 | E-MTAB-7805 | biostudies-arrayexpress
TranscriptomicsRole of Blimp-1 in programing Th effector cells into IL-10 producers
Gene expression profiling on IL-10-secreting and non-secreting murine Th1 cells, stimulated in the presence or absence of the Notch ligand Delta-like 4 (Dll4), was performed to identify transcription factors co-expressed with IL-10. Primary naM-CM-/ve T helper cells were isolated from lymph nodes an...
ORGANISM(S): Mus musculus 
2014-05-08 | E-GEOD-57417 | biostudies-arrayexpress
GenomicsRegulation of TFR cells by Blimp1
Regulation of TFR cells by Blimp1
PRJNA599098 | ENA
TranscriptomicsExpression data from mouse ALDH1 positive and ALDH1 negative ovarian surface epithelium (OSE) cells
The hilum region of the mouse ovary, the transitional/junction area between OSE, mesothelium and tubal (oviductal) epithelium is identified as a previously unrecognized stem cell niche of the OSE. OSE cells with high ALDH1 activity have been predominantly detected in the hilum region by immunohistoc...
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-43897 | biostudies-arrayexpress
TranscriptomicsmRNA expression of Qa2+ and Qa2- CD4+ thymocytes isolated from WT and miR-142-/- mice
Developing CD4+ T-cells in the thymus mature from CD69+Qa2- cells to CD69-Qa2+ T-cells. This maturation is accombanied by increased expression of CD62L and S1PR1 in Qa2+ cells, which allows mature T-cells to emigrate from the thymus to the periphery. However, miR-142-/- mice are characterized by an ...
ORGANISM(S): Mus musculus 
2013-06-14 | E-GEOD-47909 | biostudies-arrayexpress
TranscriptomicsAntigen specific human conventional T cells (CD154+) or regulatory T cells (CD137+) directed agains A. fumigatus or Birch pollen lysate isolated from Birch pollen allergic patients or healthy controls.
Foxp3+ regulatory T cells (Treg) play a central role for tolerance against self and innocuous environmental antigens. However, the role of antigen-specificity for Treg-mediated tolerance is only incompletely understood. Here we show by direct ex vivo characterization of human CD4+ T cells, that the ...
ORGANISM(S): Homo sapiens 
2016-10-25 | E-GEOD-77018 | biostudies-arrayexpress
GenomicsAtlas of the chromatin landscape in the developing nervous system of Drosophila melanogaster - ChIPseq and ATACseq - time series of tissue specific neuroblast histone PTMs
In this study, I identify novel regulatory nodes and potential signal transduction pathways that govern neurogenic tissue specification and differentiation. The Drosophila melanogaster central nervous system develops from three columns of neuroectodermal cells that give rise to neural stem cells cal...
ORGANISM(S): Drosophila melanogaster 
2025-10-30 | E-MTAB-15767 | biostudies-arrayexpress
Sort   by:  
 Page size