Sort   by:  
 Page size 
ProteomicsA comprehensive portrait of tissue-, age- and sex-specific DNA modifications in rodents and humans
DNA damage causes genomic instability underlying many diseases, with traditional analytical approaches providing minimal insight into the spectrum of DNA lesions in vivo. Here we used untargeted chromatography-coupled tandem mass spectrometry-based adductomics (LC-MS/MS) to define the landscape of D...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2023-09-12 | PXD045311 | Pride
Adductomics Strp mrm 
TranscriptomicsInterferon Lambda Alleles Predict Innate Antiviral Immune Responses and Hepatitis C Virus Permissiveness.
Hepatitis C virus (HCV) infection can result in viral chronicity or clearance. Although host genetics and particularly genetic variation in the interferon lambda (IFNL) locus are associated with spontaneous HCV clearance and treatment success, the mechanisms guiding these clinical outcomes remain un...
ORGANISM(S): Homo sapiens 
2014-02-12 | E-GEOD-54648 | biostudies-arrayexpress
TranscriptomicsEffect of dDAVP on outer medullary gene expression in Brattleboro rats
Activation of the renal urine concentrating mechanism by vasopressin requires the coordinated regulation of multiple gene products including ion transporters, and water channels as well as regulatory proteins like protein kinases and phosphatases or enzymes involved in the energy-metabolism of the c...
ORGANISM(S): Rattus norvegicus 
2012-03-01 | E-GEOD-34225 | biostudies-arrayexpress
UnknownPhase I trial and pharmacokinetic study of lexatumumab in pediatric patients with solid tumors.
Not available
S-EPMC3494837 | biostudies-literature
TranscriptomicsTranscription Profiling of Human Aortic Endothelial Cells After Treatment with Interferon-Alpha
Systemic Lupus Erythematosus is associated with an increased risk of cardiovascular disease (CVD). Interferon-response genes have been associated with endothelial dysfunction in SLE patients. The aim of this study is to identify the effects of IFN-alpha on human endothelial cells in order to deter...
ORGANISM(S): Homo sapiens 
2013-09-11 | E-MEXP-3746 | biostudies-arrayexpress
TranscriptomicsmRNA expression of Qa2+ and Qa2- CD4+ thymocytes isolated from WT and miR-142-/- mice
Developing CD4+ T-cells in the thymus mature from CD69+Qa2- cells to CD69-Qa2+ T-cells. This maturation is accombanied by increased expression of CD62L and S1PR1 in Qa2+ cells, which allows mature T-cells to emigrate from the thymus to the periphery. However, miR-142-/- mice are characterized by an ...
ORGANISM(S): Mus musculus 
2013-06-14 | E-GEOD-47909 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in mouse kidney following 72 hours of colistin exposure by Illumina WG-6_V2 array
Colistin sulfate (polymixin E) is an antibiotic prescribed with resurging frequency for multidrug resistant gram negative bacterial infections. It is associated with nephrotoxicity in humans in up to 33% of cases. Little is known regarding genes involved in colistin nephrotoxicity. A murine model o...
ORGANISM(S): Mus musculus 
2013-11-05 | E-GEOD-46410 | biostudies-arrayexpress
TranscriptomicsRNA-seq of wild-type mouse embryonic stem cells (mESC) during spontaneous differentiation
Transcriptomic analysis of mouse embryonic stem cells (mESC) maintained in the pluripotent state or allowed to differentiate for 3 or 7 days by leukaemia inhibitory factor (LIF) withdrawal.
ORGANISM(S): Mus musculus 
2023-05-27 | E-MTAB-9261 | biostudies-arrayexpress
UnknownGut Microbial Metabolites Induce Donor-Specific Tolerance of Kidney Allografts through Induction of T Regulatory Cells by Short-Chain Fatty Acids.
Not available
S-EPMC7350991 | biostudies-literature
ProteomicsGlobal identification of biofilm-specific proteolysis in Candida albicans
The global extracellular protease substrate specificity of C. albicans under biofilm and planktonic (suspension) conditions was determined with a synthetic library of 14-mer peptide substrates using an approach termed Multiplex Substrate Profiling by Mass Spectrometry (MSP-MS). Shotgun proteomics an...
ORGANISM(S): Candida Albicans (ncbitaxon:5476) 
2016-03-09 | MSV000079564 | MassIVE
Sort   by:  
 Page size