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GenomicsChIP-seq analysis of histone modifications and RNA polymerase II at 4 stages of directed cardiac differentiation of mouse embryonic stem cells
We interrogated the genome-wide occupancy of histone modifications and RNA polymerase II at several stages of an mouse embryonic stem cell to cardiomyocyte directed differentiation protocol. These four stages represent timepoints when differentiating cultures are enriched for embryonic stem cells (...
ORGANISM(S): Mus musculus 
2013-06-15 | E-GEOD-47949 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of global RNA levels at 4 stages of directed cardiac differentiation of mouse embryonic stem cells
We interrogated the transcriptome using RNA-seq at several stages of an mouse embryonic stem cell to cardiomyocyte directed differentiation protocol. These four stages represent timepoints when differentiating cultures are enriched for embryonic stem cells (ESC), mesodermal cells (MES), cardiac prec...
ORGANISM(S): Mus musculus 
2013-06-15 | E-GEOD-47948 | biostudies-arrayexpress
TranscriptomicsDynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-06-15 | E-GEOD-47950 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of Mst1/2 deleted bronchiolar epithelial cells from adult mouse lungs
Mst1 and Mst2 were conditionally deleted from non-ciliated bronchiolar epithelial cells in the mature lung. Bronchiolar epithelial cells from control and Mst1/2 deleted mice were isolated by cell sorting and used for RNA-seq analysis. Scgb1a1-rtTA/tetO-Cre/Mst1;2-flx/flx (Mst1/2 D/D) mice were gene...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-61627 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of bronchosphere cultures of primary human bronchiolar epithelial cells
Primary human bronchial epithelial cells were transduced with control or hYAP(S127A) lentivirus in sphere forming conditions. Bronchospheres were harvested on day 18-20 for RNAseq analysis Passage 1 Primary HBECs from 2 independent donors were transduced with control or hYAP lentivirus. 48 hours pos...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-61626 | biostudies-arrayexpress
TranscriptomicsMicroarray of Mst1/2 deleted epithelial cells from E18.5 mouse lungs
ShhCre;Mst1/2flx/flx (Mst1/2 D/D) mice were generated to conditionally delete Mst1 and Mst2 from epithelial progenitors during lung morphogenesis. Lungs from E18.5 control and Mst1/2 D/D mice were mechanically and enzymatically dissociated to generate single cell suspension. Epcam(+) cells were is...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-61582 | biostudies-arrayexpress
UnknownEfficacy and Safety of Nivolumab Alone or in Combination With Ipilimumab in Patients With Mucosal Melanoma: A Pooled Analysis.
Not available
S-EPMC5559888 | biostudies-literature
UnknownManagement of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline.
Not available
S-EPMC6481621 | biostudies-literature
GenomicsMolecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases
There is a critical need to improve our understanding of the pathogenesis of -melanoma brain metastases (MBM). Thus, we performed RNA sequencing on 88 resected MBMs and 42 patient-matched extracranial metastases; tumors with sufficient tissue also underwent whole-exome sequencing, T-cell receptor se...
EGAS00001003672 | EGA
GenomicsHost genotyping data from Dutch adult bacterial meningitis patients and linked bacterial genome sequences
Streptococcus pneumoniae is a common nasopharyngeal colonizer, but can also cause life-threatening invasive diseases such as empyema, bacteremia and meningitis. Genetic variation of host and pathogen is known to play a role in invasive pneumococcal disease, though to what extent is unknown. This st...
EGAS00001005993 | EGA
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