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MetabolomicsTranscriptomics and Metabolomics Reveal Alterations in Xenobiotic Metabolism and Appearance of Steroidal Alkaloid Metabolites in Mouse Livers after Tomato Consumption

SCOPE: Tomato consumption is associated with many health benefits including lowered risk for developing certain cancers. It is hypothesized that tomato phytochemicals are transported to the liver and other tissues where they alter gene expression in ways that lead to favorable he...

2023-06-13 | MTBLS6715 | MetaboLights
TranscriptomicsRegulation of alkaloid biosynthesis by miRNAs in opium poppy
MicroRNAs (miRNA) are ~21 nucleotide long, small endogenous non-coding RNAs that functioning in regulation of gene expression found in many eukaryotes. In this study, small RNA libraries of opium poppy from four different tissues (leaf, root, capsule, stem) were sequenced using high-throughput next ...
ORGANISM(S): Papaver somniferum 
2014-12-15 | E-GEOD-62716 | biostudies-arrayexpress
TranscriptomicsComparative analysis of Papaver somniferum genotypes having contrasting latex and alkaloid profiles
Sampada and Sujata are two contrasting genotypes of Papaver somniferum that are contrasting in terms of their latex and alkaloid profiles. The major objective of the present study was to use a small-scale (750 target genes) microarray of P. somniferum for identification of genes that are differentia...
ORGANISM(S): Papaver somniferum 
2013-12-30 | E-GEOD-37983 | biostudies-arrayexpress
GenomicsRAP2-7 DAP-seq (Lupinus angustifolius L.)
In this study we used DNA affinity purification sequencing (DAP-seq) to identify genome-wide binding of allele-specific RAP2-7 transcription factor variants in five narrow-leafed lupin (Lupinus angustifolius L.) genotypes with contrasting alkaloid regulation, including low-alkaloid iucundus line (83...
ORGANISM(S): Lupinus angustifolius 
2026-06-30 | E-MTAB-16430 | biostudies-arrayexpress
TranscriptomicsIllumina RNA-seq of Lupinus angustifolius L. leaf and stem transcriptomes
The aim of this experiment was to compare gene expression in leaves and stems of narrow-leafed lupin (Lupinus angustifolius L.) using Illumina RNA sequencing. Total RNA was isolated from leaves and stems of five narrow-leafed lupin (Lupinus angustifolius L.) genotypes with contrasting alkaloid regul...
ORGANISM(S): Lupinus angustifolius 
2026-06-30 | E-MTAB-16431 | biostudies-arrayexpress
TranscriptomicsPacBio Iso-seq of Lupinus angustifolius L. leaf and stem transcriptomes
The aim of this experiment was to obtain full length transcript sequences of genes expressed in leaves and stems of narrow-leafed lupin (Lupinus angustifolius L.) using PacBio Iso-Seq. Total RNA was isolated from leaves and stems of five narrow-leafed lupin (Lupinus angustifolius L.) genotypes with ...
ORGANISM(S): Lupinus angustifolius 
2026-06-30 | E-MTAB-16429 | biostudies-arrayexpress
ProteomicsStappia 28M-7 - Three new deep-sea bacteria isolated from Atlantic sponges and evidence for the biosynthesis of the antimicrobial thiazole alkaloid agrochelin
OSMAC guided bioprospecting of Atlantic sponges reveals novel bacterial species and evidence for the antimicrobial thiazole alkaloid agrochelin II A tandem mass spec data file from the crude extract of Stappia 28M-7 Taxonomy ID: 2762596
ORGANISM(S): Stappia (ncbitaxon:152161) 
2025-08-11 | MSV000098784 | MassIVE
GenomicsIndependent evolution of ipecac alkaloid biosynthesis
ipecac alkaloid biosynthesis
PRJEB80476 | ENA
GenomicsRegulation of alkaloid biosynthesis by miRNAs in opium poppy
MicroRNAs (miRNA) are ~21 nucleotide long, small endogenous non-coding RNAs that functioning in regulation of gene expression found in many eukaryotes. In this study, small RNA libraries of opium poppy from four different tissues (leaf, root, capsule, stem) were sequenced using high-throughput next ...
ORGANISM(S): Papaver somniferum synthetic construct 
2014-12-15 | GSE62716 | GEO
MetabolomicsHigh-Throughput Detection of an Alkaloidal Plant Metabolome in Plant Extracts Using LC-ESI-QTOF-MS.
Plant alkaloids represent a diverse group of nitrogen-containing natural products. These compounds are considered valuable in drug discovery and development. High-throughput identification of such plant secondary metabolites in complex plant extracts is essential for drug discovery, lead optimizatio...
2023-12-12 | MTBLS2914 | MetaboLights
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