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ProteomicsBidirectional Control of Coronary Vascular Resistance by Eicosanoids via a Novel GPCR
Arachidonic acid metabolites epoxyeicosatrienoates (EETs) and hydroxyeicosatetraenoates (HETEs) are important regulators of myocardial blood flow and coronary vascular resistance (CVR), but their mechanisms of action are not fully understood. We identified G protein-coupled receptor 39 (GPR39) as a ...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-13 | PXD013952 | Pride
Proteomics Eicosanoids G-coupled receptor 39 Microvascular smooth muscle cell Cardiovascular disease Photoactive cross-linking 
ProteomicsPhosphoproteomic Response of Cardiac Endothelial Cells to Ischemic Injury and Ultrasound
Global and phosphoproteomic data from mouse primary cardiac endothelial cells treated with oxygen deprivation and/or ultrasound. Samples were digested with trypsin, then analyzed by LC-MS/MS. Data was searched with MS-GF+ using PNNL's DMS processing pipeline.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-12-31 | MSV000086652 | MassIVE
ProteomicsHDL proteome remodeling post-stroke
Prospective cohort studies and meta-analyses examining the relationship between HDL-cholesterol (C) and stroke risk are discordant and question the value of HDL-C as a marker for stroke risk prediction. However, the relationship between other metrics of HDL, function and proteome, and stroke remain ...
ORGANISM(S): Homo Sapiens 
2021-01-24 | PXD015001 | panorama
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