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MetabolomicsChanges in lipid profiles of epileptic mouse model

INTRODUCTION: Approximately 1% of the world's population is impacted by epilepsy, a chronic neurological disorder characterized by seizures. One-third of epileptic patients are resistant to AEDs, or have medically refractory epilepsy (MRE). One non-invasive treatment that exists...

2022-01-06 | MTBLS1432 | MetaboLights
UnknownEnhanced cerebellar myelination with concomitant iron elevation and ultrastructural irregularities following prenatal exposure to ambient particulate matter in the mouse.
Not available
S-EPMC6400059 | biostudies-literature
UnknownDevelopmental exposures to ultrafine particle air pollution reduces early testosterone levels and adult male social novelty preference: Risk for children's sex-biased neurobehavioral disorders.
Not available
S-EPMC6456267 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation and RNA-seq analysis in purified quiescent yeast cells to identify the genomic RNA polymerase II and histone H3 methylation occupancy profiles and the quiescent cell transcriptome.
A defining characteristic of quiescent cells is their low level of gene activity compared to growing cells. Using a yeast model for cellular quiescence, we compared the genome-wide profiles of multiple histone modifications between growing and quiescent cells, and correlated these profiles with the...
ORGANISM(S): Saccharomyces cerevisiae 
2016-09-01 | E-GEOD-72650 | biostudies-arrayexpress
UnknownPotential frameworks to support evaluation of mechanistic data for developmental neurotoxicity outcomes: A symposium report.
Not available
S-EPMC7160758 | biostudies-literature
UnknownCITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation.
Not available
S-EPMC8581166 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation and RNA-seq analysis in purified quiescent yeast cells to identify the genomic RNA polymerase II and histone H3 methylation occupancy profiles and the transcriptome
A defining characteristic of quiescent cells is their low level of gene activity compared to growing cells. Using a yeast model for cellular quiescence, we compared the genome-wide profiles of multiple histone modifications between growing and quiescent cells, and correlated these profiles with the...
ORGANISM(S): Saccharomyces cerevisiae 
2015-09-09 | E-GEOD-72802 | biostudies-arrayexpress
TranscriptomicsHuman lupus netting neutrophils induce endothelial damage, infiltrate tissues and expose immunostimulatory molecules
Our group has proposed that low-density granulocytes (LDGs) play an important role in lupus pathogenesis, as they can damage endothelial cells and synthesize increased levels of proinflammatory cytokines and type I interferons. LDGs have a heightened capacity to synthesize neutrophil extracellular t...
ORGANISM(S): Homo sapiens 
2011-06-22 | E-GEOD-26975 | biostudies-arrayexpress
UnknownIdentical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes.
Not available
S-EPMC6341285 | biostudies-literature
UnknownA Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk.
Not available
S-EPMC6105323 | biostudies-literature
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