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TranscriptomicsTranscription profiling of human skin during elicitation of allergic contact dermatitis - time series
Genes involved in the inflammatory response resulting in allergic contact dermatitis (ACD) are only partly known. In this study, we introduce the use of high density oligonucleotide arrays for gene expression profiling in human skin during the elicitation of ACD. Skin biopsies from normal and nickel...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6281 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity
We evaluated cutaneous contact hypersensitivity (CHS) in Cnr1-/-/Cnr2-/- animals using the obligate contact allergen 2,4-dinitrofluorobenzene (DNFB), which generates a specific cutaneous T-cell mediated allergic response upon repeated allergen contact. Allergic contact dermatitis affects about 5% of...
ORGANISM(S): Mus musculus 
2009-04-23 | E-GEOD-7694 | biostudies-arrayexpress
TranscriptomicsIntegrative analysis of miRNA/mRNA expression patterns in allergic contact dermatitis
Allergic and irritant contact dermatitis induces different immunological cascades, involving a plethora of immune cells as well as keratinocytes. This highly interwoven network is regulated by miRNAs. However, which miRNAs are involved during allergic- and irritant-induced contact dermatitis is not ...
ORGANISM(S): Homo sapiens 
2020-07-01 | E-MTAB-9051 | biostudies-arrayexpress
TranscriptomicsIntegrative analysis of miRNA/mRNA expression patterns in allergic contact dermatitis
Allergic and irritant contact dermatitis induces different immunological cascades, involving a plethora of immune cells as well as keratinocytes. This highly interwoven network is regulated by miRNAs. However, which miRNAs are involved during allergic- and irritant-induced contact dermatitis is not ...
ORGANISM(S): Homo sapiens 
2020-07-01 | E-MTAB-9026 | biostudies-arrayexpress
TranscriptomicsNickel-induced contact dermatitis induce changes in human skin transcriptome over 96 hours
We aimed to characterize transcriptomic changes over time (baseline, 2 hours, 48 hours and 96 hours) after nickel-induced contact dermatitis in 6 human probands. As a contrast, 7 patients with SLS-induced irritant contact dermatitis were included. Therefore, the patch tests were applied onto the bac...
ORGANISM(S): Homo sapiens 
2020-05-01 | E-MTAB-8945 | biostudies-arrayexpress
TranscriptomicsMachine learning driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis
Allergic and irritant contact dermatitis induces different immunological cascades, involving a plethora of immune cells as well as keratinocytes. 96 patients were investigated using mRNA microarray experiments, of which 88 passed our QC criteria. Patients were topically exposed to allergens (nickel ...
ORGANISM(S): Homo sapiens 
2020-09-01 | E-MTAB-9501 | biostudies-arrayexpress
UnknownChromium(III) release from chromium-tanned leather elicits allergic contact dermatitis: a use test study.
Not available
S-EPMC5901407 | biostudies-literature
UnknownAllergic contact dermatitis caused by glucose sensors and insulin pumps: A full review: Part 2. Case reports and case series, clinical features, patch test procedures, differentiation from irritant dermatitis, management of allergic patients and (proposed) legislation.
Not available
S-EPMC11795346 | biostudies-literature
UnknownEuropean Surveillance System on Contact Allergies (ESSCA): Contact allergies in relation to body sites in patients with allergic contact dermatitis.
Not available
S-EPMC6590142 | biostudies-literature
GenomicsMolecular analysis in SADBE-induced ACD (Allergic contact dermatitis) model
Molecular analysis in SADBE-induced ACD (Allergic contact dermatitis) model
PRJNA639957 | ENA
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