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MetabolomicsUmbilical cord blood metabolome differs in relation to delivery mode, birth order and sex, maternal diet and possibly future allergy development in rural children
Allergy is one of the most common diseases among young children yet all factors that affect development of allergy remain unclear. In a small cohort of 65 children living in the same rural area of south-west Sweden, we have previously found that maternal factors, including prenatal diet, affect chil...
2020-12-18 | MTBLS2017 | MetaboLights
MetabolomicsIntegrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE‐mediated pediatric cow's milk allergy

BACKGROUND: IgE-mediated cow's milk allergy (IgE-CMA) is one of the first allergies to arise in early childhood and may result from exposure to various milk allergens, of which β-lactoglobulin (BLG) and casein are the most important. Understanding the underlying mechanisms behin...

2024-02-15 | MTBLS6768 | MetaboLights
MetabolomicsFecal metabolome alterations in infants at risk of developing allergy during the first year of life

Background: Disturbances in the gut microbiome (GM) during the first year of life may contribute to allergy risk. This period is characterized by rapid microbial colonization, influenced by factors like delivery mode and infant feeding practices. This study investigates changes in key GM taxa and...

2026-06-09 | MTBLS12775 | MetaboLights
MetabolomicsStool global metabolite levels in peanut allergy (Part 2)
Not available
ORGANISM(S): Homo sapiens 
ST002405 | MetabolomicsWorkbench
MetabolomicsStool short chain fatty acid (SCFA) levels in peanut allergy
Not available
ORGANISM(S): Homo sapiens 
ST002355 | MetabolomicsWorkbench
MetabolomicsExploring the Fecal Metabolome in Infants With Cow's Milk Allergy: The Distinct Impacts of Cow's Milk Protein Tolerance Acquisition and of Synbiotic Supplementation.

SCOPE: Cow's milk allergy (CMA) is one of the most prevalent food allergies in early childhood, often treated via elimination diets including standard amino acid-based formula or amino acid-based formula supplemented with synbiotics (AAF or AAF-S). This work aimed to assess ...

2024-09-02 | MTBLS8954 | MetaboLights
TranscriptomicsInduction of Interleukin-9-producing Mucosal Mast cells Promotes Susceptibility to IgE-mediated Experimental Food Allergy
Experimental IgE-mediated food allergy depends on intestinal anaphylaxis driven by interleukin (IL)-9. However, the primary cellular source of IL-9 and the mechanisms underlying the susceptibility to food-induced intestinal anaphylaxis remain unclear. Herein, we have reported the identification of m...
ORGANISM(S): Mus musculus 
2015-09-11 | E-GEOD-72921 | biostudies-arrayexpress
TranscriptomicsA module-based translational strategy shows a central role for S100A4 in allergy
The involvement of thousands of genes complicates the identification of clinically relevant candidate genes in common diseases. We hypothesized that genes co-regulated with a key gene in allergy, IL13, would form a module that could help to discover novel candidate genes. We identified a Th2 cell mo...
ORGANISM(S): Homo sapiens 
2014-02-05 | E-GEOD-46333 | biostudies-arrayexpress
TranscriptomicsDistinct epithelial gene expression phenotypes in childhood respiratory allergy
This SuperSeries is composed of the following subset Series: GSE19182: Gene expression profiling of differentiated HNECs stimulated by IL4, IL13, IFNalpha, IFNbeta, IFNgamma and controls GSE19187: Nasal epithelium gene expression profiling in child respiratory allergic disease Refer to individual Se...
ORGANISM(S): Homo sapiens 
2012-01-05 | E-GEOD-19190 | biostudies-arrayexpress
UnknownPollen-Food Allergy Syndrome in Korean Pollinosis Patients: A Nationwide Survey.
Not available
S-EPMC6182195 | biostudies-literature
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