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Transcriptomicschromatin reprogramming and differential gene expression in a model of EMT (spheroid A549 treated with TGF/TNF)
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-09-12 | E-GEOD-42375 | biostudies-arrayexpress
TranscriptomicsGene expression analysis in TGFbeta/TNFalpha treated A549 spheroid cultures
TGFbeta/TNFalpha treated spheroid A549 cultures are a model of the epithelial-mesenchymal transition (EMT). These experiments capture the changes in global gene expression that result from cells being induced to undergo EMT (3D control vs 3D treated), but also the differences in gene expression when...
ORGANISM(S): Homo sapiens 
2013-09-12 | E-GEOD-42373 | biostudies-arrayexpress
GenomicsHistone modification analysis in TGFbeta/TNFalpha treated A549 spheroid cultures
We studied the extent of chromatin remodeling in an in-vitro model of the epithelial-mesenchymal transition (EMT). EMT is induced in spheroid cultures (3D) using simultaneously two cytokines: TGFbeta and TNFalpha. The epithelial-mesenchymal transition (EMT) is a cellular de-differentiation process t...
ORGANISM(S): Homo sapiens 
2013-09-12 | E-GEOD-42374 | biostudies-arrayexpress
UnknownRAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome-associated cardiac hypertrophy.
Not available
S-EPMC10348673 | biostudies-literature
UnknownCharacterization of Pulmonary Metastases in Children With Hepatoblastoma Treated on Children's Oncology Group Protocol AHEP0731 (The Treatment of Children With All Stages of Hepatoblastoma): A Report From the Children's Oncology Group.
Not available
S-EPMC5648177 | biostudies-literature
GenomicsMethylation_450K_EpiMatch - samples
BLUEPRINT EpiMatch: harnessing epigenetics for hematopoietic stem cell transplantation
EGAD00010000831 | EGA
GenomicsBLUEPRINT DNA methylation profiles of graft donors in allogenic hematopoietic stem cell transplantation
Allogenic hematopoietic stem cell transplantation (HSCT) is a curative treatment for many hematological conditions. Acute graft-versus-host disease (aGVHD) is a prevalent immune-mediated complication following HSCT. Current diagnostic biomarkers that correlate with aGVHD severity, progression, and t...
EGAS00001001287 | EGA
GenomicPancreatic Cancer Cohort and Case-Control Consortium (PanScan)

Within the framework of the NCI-sponsored Cohort Consortium, investigators from 12 prospective epidemiologic cohorts formed the Pancreatic Cancer Cohort Consortium in 2006. This study, also known as "PanScan", is funded by the National Cancer Institute (NCI) and involves conducting a geno...

phs000206 | dbGaP
GenomicWhole Genome Association Study of Visceral Adiposity in the HABC Study

The Health Aging and Body Composition (Health ABC) Study is a NIA-sponsored cohort study of the factors that contribute to incident disability and the decline in function of healthier older persons, with a particular emphasis on changes in body composition in old age. Between 4/15/97 and 6...

phs000169 | dbGaP
UnknownEffectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial.
Not available
S-EPMC10698555 | biostudies-literature
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