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TranscriptomicsTranscription profiling of mouse cartilage tumours IGFBP-3 reveals is regulated by Gli signaling in cartilage tumors.
Mice that develop benign cartilage lesions due to overexpression of Gli2 in chondrocytes developed lesions similar to chondrosarcomas when also deficient in p53. Gli2 overexpression and p53 deficiency had opposing effects on chondrocyte differentiation, but had additive effects negatively regulatin...
ORGANISM(S): Mus musculus 
2009-03-14 | E-GEOD-15118 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse skin scar after wounding
Using a TCF reporter mouse which contain a LacZ gene downstream of a c-fos minimal promoter and three consensus TCF-binding motifs, we wounded skin and harvested the scar tissue one week post wounding. Healing tissue sorted to group of cells : β-Gal+ cells (R) expression data with β-Gal- cells (L)...
ORGANISM(S): Mus musculus 
2011-07-25 | E-GEOD-30913 | biostudies-arrayexpress
TranscriptomicsAffymetric 1.0 ST exon array comparing gene expression of bone marrow derived macrophage lacking beta-catenin with control macrophages
Bone marrow derived macrophages of Lysz-Cre;Catnbtm2Kem(fl/fl) mouse were compared with bone marrow derived macrophage of Catnbtm2Kem(fl/fl) control mouse Total RNA extracted from bone marrow derived macrophage
ORGANISM(S): Mus musculus 
2014-02-01 | E-GEOD-52163 | biostudies-arrayexpress
Transcriptomicshuman aggressive fibromatosis tumors
This study examines the expression profile of cells from human aggressive fibromatosis tumors. Cells from human aggressive fibromatosis tumors were manually minced, and visible clumps were removed. Enzymatic digestion using 10 mg/mL of collagenase IV, 2.4 units/mL Dispase, 0.05% trypsin, was used ...
ORGANISM(S): Homo sapiens 
2014-12-22 | E-GEOD-23356 | biostudies-arrayexpress
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