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TranscriptomicsAutism and increased paternal age related changes in global levels of gene expression regulation
A causal role of mutations in genes encoding for multiple general transcription factors in neurodevelopmental disorders including autism suggested that alterations at the global level of gene expression regulation might also relate to disease risk in sporadic cases of autism. This premise can be tes...
ORGANISM(S): Homo sapiens 
2011-10-08 | E-GEOD-25507 | biostudies-arrayexpress
TranscriptomicsTranscriptional effects of CTGF inhibition in a transgenic mouse model of dilated cardiomyopathy
Cardiac structural changes associated with dilated cardiomyopathy (DCM) include cardiomyocyte hypertrophy and myocardial fibrosis. Connective Tissue Growth Factor (CTGF) has been associated with tissue remodeling and is highly expressed in failing hearts. To test if inhibition of CTGF would alter ...
ORGANISM(S): Mus musculus 
2015-11-20 | E-GEOD-68857 | biostudies-arrayexpress
UnknownAutologous reconstitution of human cancer and immune system in vivo.
Not available
S-EPMC5356779 | biostudies-literature
UnknownMyocardial tissue deformation is reduced in subjects with coronary microvascular dysfunction but not rescued by treatment with ranolazine.
Not available
S-EPMC5436931 | biostudies-literature
TranscriptomicsMismatch oligonucleotides in yeast
Tiled 10kb region centered around ACT1 gene (YFL039C, CHROMOSOME 6 @ coords 48760-59195), double-stranded, 36mers at 1bp spacing, with mismatches and deletions; also tiled 6 genes of interest (YBL092W, YGR155W, YOL040C, YOR312C, YMR242C, YLR229C), coding strand only, 36mers at 1bp spacing, with some...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-05 | E-GEOD-13174 | biostudies-arrayexpress
GenomicsAcquired Copy Number Alterations in Adult Acute Myeloid Leukemia Genomes

We performed genome-wide copy number analysis with paired normal and tumor DNA obtained from 86 adult patients with de novo AML using the Affymetrix Genome-Wide Human SNP array 6.0 containing 1.85 million features. Acquired copy number alterations (CNA) were confirmed using an independent, hig...

phs000201.v1.p1 | EGA
UnknownLoss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19.
Not available
S-EPMC7437499 | biostudies-literature
UnknownNew York Heart Association functional class predicts exercise parameters in the current era.
Not available
S-EPMC2762947 | biostudies-literature
UnknownMeta-analysis of Parkinson's disease: identification of a novel locus, RIT2.
Not available
S-EPMC3354734 | biostudies-literature
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