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ProteomicsAn optimized proteomics approach reveals novel alternative proteins in mouse liver development
Alternative open reading frames (AltORFs) are unannotated sequences in genome that encode novel peptides or proteins named alternative proteins (AltProts). Although ribosome profiling and bioinformatics predict a large number of AltProts, mass spectrometry (MS) as the only direct way of identificati...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-23 | PXD033940 | Pride
Liver development. Mass spectrometry Fractionation Alternative open reading frames (altorfs) Alternative proteins (altprots) Enrichment 
UnknownDirect detection of alternative open reading frames translation products in human significantly expands the proteome.
Not available
S-EPMC3741303 | biostudies-literature
UnknownThe Protein Coded by a Short Open Reading Frame, Not by the Annotated Coding Sequence, Is the Main Gene Product of the Dual-Coding Gene MIEF1.
Not available
S-EPMC6283296 | biostudies-literature
ProteomicsFirst evidence that a protein coded by a short ORF, not by the annotated CDS is the main gene product
Proteogenomics and ribosome profiling concurrently show that genes may code for both a large and one or more small proteins translated from annotated coding sequences (CDSs) and unannotated alternative open reading frames (named alternative ORFs or altORFs), respectively, but the stoichiometry betwe...
ORGANISM(S): Homo sapiens (Human) 
2018-11-21 | PXD008147 | Pride
Crispr-cas9 Short orf Targeted proteomics Translation 
UnknownIn-Depth Annotation of the Drosophila Bithorax-Complex Reveals the Presence of Several Alternative ORFs That Could Encode for Motif-Rich Peptides.
Not available
S-EPMC8616405 | biostudies-literature
UnknownDeep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins.
Not available
S-EPMC5703645 | biostudies-literature
UnknownPotentiation of B2 receptor signaling by AltB2R, a newly identified alternative protein encoded in the human bradykinin B2 receptor gene.
Not available
S-EPMC7949122 | biostudies-literature
UnknownA small protein coded within the mitochondrial canonical gene nd4 regulates mitochondrial bioenergetics.
Not available
S-EPMC10193809 | biostudies-literature
UnknownNoncanonical altPIDD1 protein: unveiling the true major translational output of the PIDD1 gene.
Not available
S-EPMC11557682 | biostudies-literature
UnknownThe dual-coding gene SLC35A4 protects against oxidative stress.
Not available
S-EPMC12183330 | biostudies-literature
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