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MetabolomicsMetabolome analysis via an HPLC-ESI-MS-based experimental and computational pipeline for chronic nephron toxicity profiling
Untargeted metabolomics has the potential to improve the predictivity of in vitro toxicity models and therefore may aid the reduction of expensive and laborious animal models. Here we describe a chronic nephrotoxicity study conducted on a human renal proximal tubular epithelial cell line (RPTEC/TERT...
2015-09-07 | MTBLS140 | MetaboLights
GenomicsAnalysis of transcriptome response of rhizobia to aluminium toxicity
Analysis of transcriptome response of rhizobia to aluminium toxicity
PRJNA796593 | ENA
TranscriptomicsTranscriptional profiling of aluminum toxicity and tolerance responses in maize roots
Aluminum (Al) toxicity is a major factor limiting crop yields on acid soils. In maize, Al tolerance is a complex phenomenon involving multiple genes and physiological mechanisms yet uncharacterized. To begin elucidating the molecular basis of maize Al toxicity and tolerance, we performed a detailed ...
ORGANISM(S): Zea mays 
2010-05-26 | E-GEOD-10308 | biostudies-arrayexpress
TranscriptomicsAnalysis of transcriptome response of rhizobia to aluminium toxicity
Purpose: High throughput sequencing has revolutionized methods of microbial pathway analysis in response to various envoronmental stimuli. The aim of this study was to determine mechanisms in which Rhizobium phaseoli employ towards tolerance or resistance to aluminium toxicity through RNA sequencing...
ORGANISM(S): Rhizobium phaseoli 
2022-01-17 | GSE193556 | GEO
TranscriptomicsSilver Nanowire Exposure Results in Internalization and Toxicity to Daphnia magna
Nanowires (NWs), high-aspect-ratio nanomaterials, are increasingly used in technological materials and consumer products and may have toxicological characteristics distinct from nanoparticles. We carried out a comprehensive evaluation of the physicochemical stability of four silver nanowires (AgNWs)...
ORGANISM(S): Daphnia magna 
2013-12-31 | E-GEOD-47064 | biostudies-arrayexpress
UnknownChemical-genomic profiling identifies genes that protect yeast from aluminium, gallium, and indium toxicity.
Not available
S-EPMC10233895 | biostudies-literature
TranscriptomicsAluminum-inducible genes
Aluminum (Al) toxicity, which is caused by the solubilization of Al3 in acid soils resulting in inhibition of root growth and nutrient/water acquisition, is a serious limitation to crop production, because up to one-half of the world?s potentially arable land is acidic. To date, however, no Al tole...
ORGANISM(S): Arabidopsis thaliana 
2007-08-09 | E-GEOD-7582 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis plants after treatment with aluminum
Aluminum (Al) toxicity, which is caused by the solubilization of Al3 in acid soils resulting in inhibition of root growth and nutrient/water acquisition, is a serious limitation to crop production, because up to one-half of the world?s potentially arable land is acidic. To date, however, no Al tole...
ORGANISM(S): Arabidopsis thaliana 
2007-05-04 | E-SMDB-4017 | biostudies-arrayexpress
ProteomicsArabidopsis CASEIN KINASE 2 controls Aluminium toxicity and phosphate deficiency through control of the DNA damage response
Aluminum (Al) toxicity and phosphate (Pi) limitation are widespread chronic abiotic and mutually enhancing stresses that profoundly affect crop yield. Both stresses causes a strong inhibition of root growth due to a progressive exhaustion of the stem cell niche. Here we report on a CASEIN KINASE 2 (...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-03-29 | PXD018727 | Pride
Phosphate limitation Arabidopsis Aluminium toxicity Casein kinase 2 Dna damage response 
UnknownRoot adaptations to soils with low fertility and aluminium toxicity.
Not available
S-EPMC5055624 | biostudies-literature
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