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TranscriptomicsPitx1 Haploinsufficiency Causes Clubfoot in Humans and Mice
To identify genes regulated by Pitx1 during early hindlimb development, we compared gene expression differences between hindlimb buds from E12.5 Pitx1+/+ and Pitx1-/- mice on the Illumina MouseRef-8 expression Bead Chip. Genes involved in muscle development GeneGO processes were highly enriched in ...
ORGANISM(S): Mus musculus 
2011-11-21 | E-GEOD-27363 | biostudies-arrayexpress
TranscriptomicsDissociated avian utricle sensory epithelia treated with one of various siRNAs or small molecule inhibitors
The inner ear utilizes sensory hair cells as mechano-electric transducers for sensing sound and balance. In mammals, these sensory hair cells lack the capacity for regeneration and if damaged lead to hearing or balance disorders. However, non-mammalian vertebrates such as birds maintain their regene...
ORGANISM(S): Gallus gallus 
2010-07-02 | E-GEOD-16842 | biostudies-arrayexpress
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