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TranscriptomicsExpression data of influenza A-infected human type I-like alveolar epithelial cells
Pandemic influenza H1N1 (pdmH1N1) virus causes mild disease in humans but occasionally leads to severe complications and even death, especially in those who are pregnant or have underlying disease. Cytokine responses induced by pdmH1N1 viruses in vitro are comparable to other seasonal influenza viru...
ORGANISM(S): Homo sapiens 
2010-10-06 | E-GEOD-24533 | biostudies-arrayexpress
TranscriptomicsKey Role of MicroRNA in the Regulation of Granulocyte Macrophage Colony-stimulating Factor Expression in Murine Alveolar Epithelial Cells (AEC) during Oxidative Stress
A genome wide microarray identified 19 candidate miRNA altered in primary AEC during oxidative stress with reversal by treatment with GM-CSF. Three of these microRNA (miR 133a, miR133a* and miR133b) are also predicited to bind the GM-CSF 3 UTR. 4 samples. Primary murine alveolar epithelial cells wer...
ORGANISM(S): Mus musculus 
2014-04-11 | E-GEOD-56687 | biostudies-arrayexpress
TranscriptomicsExpression data from sorted control and Pygo2-null mouse mammary stem/basal cells
Skin-mammary specific knockout (SSKO) of Pygo2 (K14-cre; Pygo2 flox/-) , a WNT signaling co-activator, results in defective mouse mammary gland development. The FACS sorted mammary stem cell (MaSC)/basal population from Pygo2 SSKO mammary gland displays biased differentiation towards luminal/alveola...
ORGANISM(S): Mus musculus 
2013-09-05 | E-GEOD-45826 | biostudies-arrayexpress
UnknownAlveolar Basal Cells Differentiate towards Secretory Epithelial- and Aberrant Basaloid-like Cells In Vitro.
Not available
S-EPMC9180703 | biostudies-literature
GenomicsHierarchal gene master regulators of adenocarcinomic human alveolar basal epithelial cells A549.
Hierarchal gene master regulators of adenocarcinomic human alveolar basal epithelial cells A549.
PRJNA478250 | ENA
TranscriptomicsTranscription profiling of human fetal lung epithelial cells in undifferentiated state and after type II cell differentiation induced by DCI treatment
Studies of human fetal lung in explant culture and in isolated epithelial cells have demonstrated that both glucocorticoids and cyclic AMP promote differentiated alveolar type II cell phenotype as assessed by ultrastructural morphology and surfactant production. This project profiles changes in gen...
ORGANISM(S): Homo sapiens 
2007-11-22 | E-GEOD-3306 | biostudies-arrayexpress
GenomicsAlveolar basal cells differentiate towards secretory epithelial and aberrant basaloid cells in vitro
Alveolar basal cells differentiate towards secretory epithelial and aberrant basaloid cells in vitro
PRJNA813874 | ENA
GenomicsFgf10-Fgfr2b signaling generates basal cells and drives alveolar epithelial regeneration by bronchial epithelial stem cells after lung injury
Fgf10-Fgfr2b signaling generates basal cells and drives alveolar epithelial regeneration by bronchial epithelial stem cells after lung injury
PRJNA529914 | ENA
TranscriptomicsmicroRNA-mediated GALNT3 upregulation facilitates mucin production and viral replication in influenza A virus-infected respiratory epithelial cells
Viral infections affecting the upper or lower respiratory tract induce mucin production in the epithelial surfaces of the respiratory cells. However, a little is known about how mucins are produced on the surfaces of respiratory epithelial cells and affects viral replication. In the course of the in...
ORGANISM(S): Homo sapiens 
2015-12-08 | E-GEOD-57508 | biostudies-arrayexpress
TranscriptomicsHigh throughput quantitative whole transcriptome analysis of distal mouse lung epithelial cells from various developmental stages (E14.5, E16.5, E18.5 and adult)
We used microfluidic single cell RNA-seq on 198 individual mouse lung epithelial cells at 4 different stages throughout development to measure the transcriptional states which define the developmental and cellular hierarchy of the distal mouse lung epithelium. We classified 80 cells comprising the d...
ORGANISM(S): Mus musculus 
2014-04-08 | E-GEOD-52583 | biostudies-arrayexpress
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