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TranscriptomicsGenome-wide analysis of high glucose and DZNep (EZH2 inhibitor) induced gene expression by mouse podocytes
Analysis of DZNep-induced gene expression changes in cultured podocytes. The hypothesis tested in the present study was that DZnep ultimately augments Txnip expression, increasing oxidative stress in podocytes. These results provide important information on the response of podocytes to histone methy...
ORGANISM(S): Mus musculus 
2015-12-09 | E-GEOD-60038 | biostudies-arrayexpress
UnknownSynthesis, Characterization, PXRD Studies, Theoretical Calculation, and Antitumor Potency Studies of a Novel N,O-Multidentate Chelating Ligand and Its Zr(IV), V(IV), Ru(III), and Cd(II) Complexes.
Not available
S-EPMC10908574 | biostudies-literature
UnknownPlacental abruption and risk for intraventricular hemorrhage in very low birth weight infants: the United States national inpatient database.
Not available
S-EPMC11442351 | biostudies-literature
TranscriptomicsHippocampal gene expression profiling of a model of Alzheimer`s Disease upon treatment with the ACE inhibitor captopril
Extracellular senile plaques of amyloid beta (Abeta) are a pathological hallmark in brain of patients with Alzheimer`s Disease (AD). Abeta is generated by the amyloidogenic processing of the amyloid precursor protein (APP). Concomitant to Abeta load, AD brain is characterized by an increase in prote...
ORGANISM(S): Mus musculus 
2013-05-14 | E-GEOD-46871 | biostudies-arrayexpress
UnknownMolecular Docking, DFT Calculations, Effect of High Energetic Ionizing Radiation, and Biological Evaluation of Some Novel Metal (II) Heteroleptic Complexes Bearing the Thiosemicarbazone Ligand.
Not available
S-EPMC8512603 | biostudies-literature
UnknownEffect of gamma irradiation on the Cu(II), Ru(III) and Pd(II) complexes of azo antipyrine moiety and their biological applications.
Not available
S-EPMC12569019 | biostudies-literature
UnknownSynthesis, characterization, PXRD studies, and theoretical calculation of the effect of gamma irradiation and antimicrobial studies on novel Pd(II), Cu(II), and Cu(I) complexes.
Not available
S-EPMC10894937 | biostudies-literature
TranscriptomicsEstablishment of a novel model to assess the function of proteins under in vivo conditions
We established a novel model to assess the function of proteins under in vivo conditions. The model relies on the expansion of HEK293 cells in immunodeficient NOD.Scid mice. To validate the novel model, we performed microarray gene expression profiling of NOD.Scid-expanded HEK293 cells relative to c...
ORGANISM(S): Homo sapiens 
2009-10-26 | E-GEOD-18739 | biostudies-arrayexpress
TranscriptomicsHost Factors with Reduced Expression in Two HCV Permissive Cell Lines as Compared to the Non-Permissive Parent Cell Line Huh7
Drugs directly targeting Hepatitis C (HCV) are often rendered useless by the high mutation rate of the virus. Thus, we deduce that targeting of host factor that affect HCV replication may provide enhanced therapy fort HCV infection. Hepatocyte cell line Huh7 is known to be non-permissive for Hepatit...
ORGANISM(S): Homo sapiens 
2011-05-01 | E-GEOD-25156 | biostudies-arrayexpress
TranscriptomicsCardiac gene expression profiling of apoE-deficient mice receiving heart failure treatment with the anti-ischemic drug ranolazine
Heart failure is a leading cause of cardiovascular mortality with limited options for treatment. We used 18 month-old apolipoprotein E (apoE)- deficient mice as a model of atherosclerosis-induced heart failure to analyze whether the anti-ischemic drug ranolazine could retard the progression of heart...
ORGANISM(S): Mus musculus 
2010-12-03 | E-GEOD-25767 | biostudies-arrayexpress
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