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TranscriptomicsRNA-seq of control and CHH (cartilage-hair hypoplasia) fibroblasts transdifferentiated into chondrocytes-like cells
We used primary human CHH (cartilage-hair hypoplasia) and control fibroblasts in a chondrogenic transdifferentiation model (FDC; fibroblast-derived chondrocytes) to determine the chondrogenic capacity and differential pathway regulation of CHH cells. For the sequencing experiment, dermal fibroblasts...
ORGANISM(S): Homo sapiens 
2021-10-09 | E-MTAB-10996 | biostudies-arrayexpress
GenomicsrRNA 2'-O-methylation profile of SNORD71 knockdown cells
We generated a SNORD71 KO chondrocyte cell pool using CRISPR/Cas9 gene editing. A CRISPR control cell line was generated and used as a control. Levels of 2’-O-methylation of human rRNAs in SNORD71 KO cell pool and CRISPR control cells were evaluated by RiboMethSeq.
ORGANISM(S): Homo sapiens 
2022-03-05 | E-MTAB-11470 | biostudies-arrayexpress
TranscriptomicsRibosomal RNA 2’-O-methylation profile of human articular chondrocytes exposed to an osteoarthritic environment
We used chondrocytes exposed to osteoarthritic synovial fluid as a chronic disease model to study the effects of a chronic disease microenvironment on 2’-O-me rRNA heterogeneity. Human non-OA human articular chondrocytes (5 individual donors) were cultured either in the presence of OA-SF (20% (v/v),...
ORGANISM(S): Homo sapiens 
2022-03-05 | E-MTAB-11469 | biostudies-arrayexpress
ProteomicsComparison of wild type and HSPG2+/- hiPSC-CMs
Investigating the effect of perlecan haploinsufficiency on cardiomyocyte differentiation
ORGANISM(S): Homo sapiens (Human) 
2025-02-26 | PXD046359 | Pride
Hspg2+/- Hipsc-cms 
ProteomicsCellular proteome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3
Cellular proteome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3 and control condition was assessed.
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD046111 | Pride
Yfgb Sw1353 Proteome 
ProteomicsRibosomal proteome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3
Ribosomal proteome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3 and control condition was assessed.
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD046114 | Pride
Ribosomal proteome Tgfb Sw1353 
ProteomicsSecretome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3
Secretome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3 and control condition was assessed.
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD046109 | Pride
Tgfb Sw1353 Secretome 
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