Alzheimer's - OmicsDI

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Organisms

Homo sapiens (543)
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human gammaherpesvirus 4 (1)

Organisms

Mus musculus (401)
Homo sapiens (363)
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mouse gut metagenome (9)
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human oral bacteria ensemble (1)
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NODE (1)

Tissue

Brain (296)
Cell culture (42)
Cerebrospinal fluid (39)
Blood plasma (18)
Microglial cell (12)
Hippocampus (9)
Blood serum (7)
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Neuron (6)
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Blood (2)
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Brain (1)
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Disease

Alzheimer's disease (307)
Normal (21)
Parkinson's disease (15)
Alzheimers disease (9)
Lewy body dementia (8)
Asymptomatic Alzheimer's disease (5)
Progressive supranuclear palsy (5)
Tauopathy (5)
Amyotrophic lateral sclerosis (3)
Pick disease (2)
Progressive supranuclear palsy (2)
Huntington's disease (2)
Mild cognitive impairment (1)
Incipient Alzheimer's disease (1)
Moderate Alzheimer's disease (1)
Severe Alzheimer's disease (1)
Genetic frontotemporal degeneration with dementia (1)
Genetic frontotemporal degeneration with FUS inclusions (1)
Pathological aging (1)
Genetic frontotemporal degeneration with TDP inclusions (1)
Corticobasal degeneration (1)
Multiple system atrophy (1)
Tangle predominant senile dementia (1)
Amyotrophic lateral sclerosis with dementia (1)
Parkinson's disease and Parkinson's disease dementia (1)
Genetic frontotemporal degeneration with ubiquitin inclusions (1)
Prion disease (1)
Cataract (1)
Autistic disorder (1)
Cardiovascular system disease (1)

Technology Type

Mass Spectrometry (474)
Shotgun proteomics (231)
Bottom-up proteomics (119)
Data-independent acquisition (56)
Data-dependent acquisition (55)
Affinity purification coupled with mass spectrometry proteomics (27)
Gel-based experiment (22)
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SWATH MS (19)
Mass spectrometry (14)
SRM/MRM (14)
DiaPASEF (10)
Mass spectrometry assay (8)
All-ion fragmentation (6)
Chemical cross-linking coupled with mass spectrometry proteomics (6)
HDMSE (5)
Mass spectrometry imaging (5)
ESI (3)
ILLUMINA, Illumina MiSeq (2)
NMR spectroscopy (2)
NMR spectroscopy assay (1)
MSE (1)

Instrument Platform

Q Exactive (25)
Q Exactive HF (18)
Illumina NovaSeq 6000 (8)
Illumina HiSeq 2500 (5)
Illumina HiSeq 4000 (4)
NextSeq 500 (4)
- (3)
BeadBug Benchtop homogenizer (2)
N/A (2)
NextSeq 2000 (2)
5-Laser BD FACSAria III (1)
Dell laptop (1)
Clariom D Human Transcriptome Arrays (Applied Biosystems, ThermoFisher) (1)
Thermal cycle, microcenrifuge, vortex mixer, pipettes (1)
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Microtome (1)
Biopsy punch (Ø 6 mm) and microtome (1)
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None (1)
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ScanArray 5000 [PerkinElmer] (1)
Illumina NovaSeq X (1)
Illumina HiSeq 1000 (1)
NextSeq 550 (1)
Illumina HiSeq 2000 (1)
Illumina HiSeq 3000 (1)

Publication Date

2025 (259)
2026 (227)
2024 (202)
2021 (167)
2023 (155)
2022 (134)
2019 (93)
2020 (85)
2014 (57)
2015 (56)
2017 (51)
2016 (50)
2018 (45)
2013 (39)
2012 (23)
2010 (22)
2011 (19)
2007 (16)
2008 (12)
2009 (10)
2006 (6)
2005 (2)
2004 (2)

UNIPROT ID/AC

P05067 (13)
P49841 (4)
P04637 (4)
P62136 (3)
Q00987 (3)
Q13315 (3)
Q9NZ42 (3)
P08473 (2)
P10636 (2)
P50148 (2)
P0CG47 (2)
P56817 (2)
Q07954 (2)
P02649 (2)
Q7KYZ4 (1)
O95816 (1)
Q71U36 (1)
Q16543 (1)
P62988 (1)
Q9UNE7 (1)
P10145 (1)
P19174 (1)
P78352 (1)
Q13554 (1)
P50391 (1)
Q03169 (1)
P17861 (1)
Q13018 (1)
P04628 (1)
Q06787 (1)

ENSEMBL ID

ENSG00000170477 (1)
ENSG00000229353 (1)
ENSMUSG00000027651 (1)
ENSMUSP00000141097 (1)

CHEBI ID

CHEBI:15422 (12)
CHEBI:16761 (12)
CHEBI:16027 (10)
CHEBI:16811 (7)
CHEBI:15611 (7)
CHEBI:17822 (6)
CHEBI:17287 (5)
CHEBI:18237 (5)
CHEBI:60425 (4)
CHEBI:26523 (4)
CHEBI:29101 (3)
CHEBI:16474 (3)
CHEBI:16908 (3)
CHEBI:16526 (3)
CHEBI:18021 (3)
CHEBI:16991 (3)
CHEBI:15361 (3)
CHEBI:15355 (3)
CHEBI:64645 (2)
CHEBI:27354 (2)
CHEBI:37455 (2)
CHEBI:25523 (2)
CHEBI:26689 (2)
CHEBI:17634 (2)
CHEBI:5656 (2)
CHEBI:17724 (2)
CHEBI:17515 (2)
CHEBI:27470 (2)
CHEBI:16842 (2)
CHEBI:1989 (2)

Metabolite Name

Taurine (7)
Creatine (7)
Leucine (6)
Pseudouridine (6)
Citrulline (5)
Guanosine (5)
Hypoxanthine (5)
Ribitol (4)
AMP (4)
ATP (4)
Uracil (4)
Carnosine (4)
Allantoin (4)
Serotonin (4)
L-Histidine (4)
DTMP (4)
Deoxycholic acid (4)
Glutathione (4)
L-Glutamic acid (4)
Myo-Inositol (4)
Glyceric acid (4)
Oxypurinol (4)
Cytosine (4)
L-Tryptophan (4)
L-Glutamine (4)
Adenine (4)
Methylmalonic acid (4)
Uric acid (4)
Xanthine (4)
Uridine (4)

First Public Date

2025 (225)
2024 (196)
2026 (185)
2023 (121)
2021 (79)
2022 (67)
2014 (62)
2020 (59)
2019 (48)
2013 (33)
2018 (26)
2017 (26)
2015 (25)
2016 (17)

Modelling Approach

Ordinary differential equation model (28)
Machine learning (1)
Mathematical model (1)
Pharmacodynamics model (1)
Constraint-based model (1)

Study status

Completed (2)

Lab affiliation

Department of Neurobiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA (11)
Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic (6)
St. Jude Children's Research Hospital (6)
DZNE Munich, Neuroproteomics, Feodor-Lynen-Str. 17, 81377 München, Germany (5)
Department of Molecular and Cellular Neurobiology, Center for Neurogenomics & Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands (5)
Division of Cardiovascular Sciences, School of Medical Science, Faculty of Biology, Medicine and Health, The University of Manchester (5)
DZNE Munich, Neuroproteomics, Feodor-Lynen Str. 17, 81377 Munich, Germany (4)
Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark (4)
Emory University School of Medicine Departments of Biochemistry and Neurology (4)
St Jude Children's Research Hospital (4)
DZNE Munich Neuroproteomics Feodor-Lynen Str. 17 81377 Munich Germany (3)
Department of Neurology, Yale School of Medicine, Yale University, new haven CT, USA (3)
Federal University of Uberlandia (3)
National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (3)
Tanz Centre for Research in Neurodegenerative Diseases, Faculty of Medicine, University of Toronto (3)
The Drug Discovery Lab, Mary S. Easton Center for Alzheimer’s Disease Research, Department of Neurology, David Geffen School of Medicine, 710 Westwood Plaza, University of California Los Angeles, Los Angeles, CA 90095, USA (3)
Vanderbilt University Department of Chemistry (3)
Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA (2)
Boston University (2)
Center for Alzheimer's and Related Dementias (CARD), NIA and NINDS, NIH, Bethesda, Maryland, USA. (2)
Center for Neurogenomics and Cognitive Research, Department of Molecular and Cellular Neurobiology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands. (2)
Chronic Disease Programme (UFIEC), Instituto de Salud Carlos III, Majadahonda, E-28220 Madrid, Spain. (2)
Chronic Disease Programme, UFIEC, Instituto de Salud Carlos III, Majadahonda, E-28220 Madrid, Spain. (2)
Dalian Institute of Chemical Physics (2)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (2)
Department of Chemistry and Biomolecular Chemistry, University of Wisconsin, Wisconsin, USA (2)
Department of Immunobiology, College of Life Science and Technology, Jinan University, Guangzhou, China. (2)
Department of Life and Environmental Sciences, University of Cagliari (2)
Department of Neuroscience of Disease, Brain Research Institute, Niigata University (2)
Department of Oncology-Pathology, Karolinska Institutet and Science for Life Laboratory, Stockholm, Sweden (2)

IsPrivate

False (33)

Model Flag

Non Kinetic (2)

Submitter Keywords

Ersilia (1)
FAIR-AIML (1)
Machine Learning Model (1)

Classification

bacteria (1)

Modification

N6 (2)
N6-dimethyl-L-lysine (2)

Study type

Transcription profiling by array (155)
RNA-seq of coding RNA (25)
Methylation profiling by array (12)
Unknown experiment type (7)
Comparative genomic hybridization by array (4)
Proteomic profiling by array (4)
RNA-seq of total RNA (4)
RNA-seq of non coding RNA (4)
ChIP-seq (3)
One-color microarray (2)
Animal - High-throughput sequencing (2)
MicroRNA profiling by high throughput sequencing (2)
RNA-seq of coding RNA from single cells (2)
Interventional (2)
Animal - One-color microarray (1)
ChIP-chip by tiling array (1)
High-throughput sequencing (1)
Human - One-color microarray (1)
Cell line - High-throughput sequencing (1)
Single nucleus RNA sequencing (1)
DNA-seq (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2025 (5828)
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2024 (4714)
2021 (4334)
2020 (3351)
2019 (2540)
2018 (2172)
2017 (1783)
2016 (1437)
2015 (1234)
2014 (992)
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2012 (544)
2011 (432)
2010 (347)
2009 (263)
2008 (163)
2007 (123)
2006 (82)
2004 (53)
2005 (48)
2003 (28)
2000 (16)
2002 (15)
2001 (13)
1999 (11)
1998 (7)
1997 (2)

Location

Canada (2)

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Urine metabolomics phenotyping and urinary biomarker exploratory in mild cognitive impairment and Alzheimer's disease.

INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

2024-01-11 | MTBLS8662 | MetaboLights

Exploring the effects of acupuncture intervention on the gut microbiota of SAMP8 mice, a model of Alzheimer's disease.

2026-02-26 | MTBLS13601 | MetaboLights

Cerebellum Alzheimer's Disease

Ion channel splice array data from cerebellum brain tissue samples collected from Alzheimer's disease patients. Temporal cortex (Alzheimer's disease affected brain tissue structure) and cerebellum (Alzheimer's disease unaffected brain tissue structure) samples from control subjects were compared to ...

ORGANISM(S): Homo sapiens

2010-06-11 | E-GEOD-6777 | biostudies-arrayexpress

Temporal Cortex Alzheimer's Disease

Ion channel splice array data from temporal cortex brain tissue samples collected from Alzheimer's disease patients. Temporal cortex (Alzheimer's disease affected brain tissue structure) and cerebellum (Alzheimer's disease unaffected brain tissue structure) samples from control subjects were compare...

ORGANISM(S): Homo sapiens

2010-06-11 | E-GEOD-6775 | biostudies-arrayexpress

Cerebellum Control (Alzheimer's disease control)

Ion channel splice array data from cerebellum brain tissue samples collected from control (non Alzheimer's disease) subjects. Temporal cortex (Alzheimer's disease affected brain tissue structure) and cerebellum (Alzheimer's disease unaffected brain tissue structure) samples from control subjects wer...

ORGANISM(S): Homo sapiens

2010-06-11 | E-GEOD-6778 | biostudies-arrayexpress

Temporal Cortex Control (Alzheimer's disease control)

Ion channel splice array data from temporal cortex brain tissue samples collected from control subjects (no Alzheimer's disease). Temporal cortex (Alzheimer's disease affected brain tissue structure) and cerebellum (Alzheimer's disease unaffected brain tissue structure) samples from control subjects...

ORGANISM(S): Homo sapiens

2010-06-11 | E-GEOD-6774 | biostudies-arrayexpress

Temporal lobe epilepsy and Alzheimer's disease

This SuperSeries is composed of the following subset Series: GSE6771: Temporal Cortex Control (mesial temporal lobe epilepsy control) GSE6773: Temporal neocortex mesial temporal lobe epilepsy GSE6774: Temporal Cortex Control (Alzheimer's disease control) GSE6775: Temporal Cortex Alzheimer's Disease ...

ORGANISM(S): Homo sapiens

2007-01-23 | E-GEOD-6834 | biostudies-arrayexpress

3,4-Dihydroxybenzaldehyde exerts anti-Alzheimer's effects by inhibiting Aβ protofibril assembly and activating antioxidant defense mechanisms

Broad-spectrum metabolomic analyses reveal that DBD markedly modulates the nematode’s metabolic profile. DBD enhances the activation of transcription factors DAF-16/FOXO and SKN-1/Nrf2, increasing resistance to oxidative and thermal stress. These findings suggest that DBD possesses multi-target t...

2025-12-24 | MTBLS13568 | MetaboLights

Determination and comparison of SCFAs in serum and colon content samples: Alzheimer's disease rat as a case study (Method validation)

SCFAs are the main microbial fermentation products from dietary fibers in colon and play a key role in keeping healthy in the whole-body. However, differences of SCFAs concentration in the serum and colon samples collected from rats had attracted few attentions. Here, we optimized the extract and...

2020-11-24 | MTBLS2146 | MetaboLights

Determination and comparison of SCFAs in serum and colon content samples: Alzheimer's disease rat as a case study (SCFA serum and colon content determination)

2020-11-24 | MTBLS2088 | MetaboLights

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INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

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