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Unknown (22305)
Genomics (773)
Transcriptomics (564)
Proteomics (494)
Other (27)
Metabolomics (27)
Methylation profiling (14)
Models (12)
Genomic (5)

Organisms

Homo sapiens (524)
Mus musculus (489)
Rattus norvegicus (34)
Drosophila melanogaster (11)
Danio rerio (10)
Saccharomyces cerevisiae (4)
Caenorhabditis elegans (4)
Mus (3)
Escherichia coli (3)
Fusarium sinicum (3)
Bos taurus (3)
Microcebus murinus (2)
Sus scrofa (2)
Punica granatum (1)
Aplysia californica (1)
Pan troglodytes (1)
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Cricetulus griseus (1)
Canis lupus familiaris (1)
Ligilactobacillus murinus (1)
synthetic construct (1)
Clostridium butyricum (1)
Enterococcus casseliflavus ATCC 49996 (1)
Escherichia coli 90.0091 (1)
Human parechovirus strain T82-0169 (1)
Klebsiella aerogenes KCTC 2190 (1)
Rattus rattus (1)
Chlorocebus aethiops (1)
Macaca fascicularis (1)
Macaca mulatta (1)

Organisms

Mus musculus (283)
Homo sapiens (220)
Rattus norvegicus (11)
Danio rerio (9)
mouse gut metagenome (6)
Ligilactobacillus murinus (3)
Drosophila melanogaster (3)
Mus (2)
human gut metagenome (2)
Sus scrofa (2)
Caenorhabditis elegans (2)
human oral bacteria ensemble (1)
Butyricimonas faecihominis (1)
Microcebus murinus (1)
synthetic construct (1)
metagenome (1)
mouse metagenome (1)
Canis lupus familiaris (1)
Mus (1)
gut metagenome (1)

Repository

ENA (703)
geo (470)
pride (328)
biostudies-arrayexpress (189)
MassIVE (99)
iProX (38)
MetaboLights (20)
EGA (16)
BioModels (12)
PanoramaPublic (12)
jPOST (10)
dbGaP (5)
GNPS (4)
GPMDB (3)
MetabolomicsWorkbench (3)
PAXDB (3)
PeptideAtlas (1)

Tissue

Brain (228)
Cell culture (24)
Cerebrospinal fluid (22)
Blood plasma (10)
Microglial cell (7)
Blood serum (5)
Hippocampus (5)
Epithelial cell (4)
Extracellular vesicle (4)
HeLa cell (4)
Retina (4)
Saliva (4)
Blood cell (3)
Hippocampal neuron (3)
Neuron (3)
Tear (3)
Blood (2)
Astrocyte (2)
Head (2)
Heart (2)
Permanent cell line cell (2)
Pyramidal neuron (2)
Spinal cord (2)
Stem cell (2)
Synapse (2)
Cerebrospinal fluid (1)
Prefrontal Cortex (1)
Astrocyte of the cerebral cortex (1)
Blood (1)
Blood platelet (1)

Disease

Alzheimer's disease (209)
Alzheimer's disease 1 (7)
Lewy body dementia (6)
Parkinson's disease (5)
Chronic traumatic encephalopathy (4)
Corticobasal degeneration syndrome (4)
Frontotemporal dementia (4)
Pick's disease (4)
Progressive supranuclear palsy (4)
Not Available (3)
Alzheimers disease (3)
Dementia (3)
Disease free (3)
Alzheimer's disease 18 (2)
Alzheimer's disease 3 (2)
Alzheimer's disease 4 (2)
Cerebral amyloid angiopathy (2)
Down syndrome (2)
Tauopathy (2)
Multiple sclerosis (1)
Neurologically healthy control (1)
Normal (1)
Neuroblastoma (1)
Alzheimer's Disease (1)
Acute leukemia (1)
Alzheimer disease (1)
Amyotrophic lateral sclerosis (1)
Brain cancer (1)
Disease (1)
Encephalopathy (1)

Technology Type

Mass Spectrometry (331)
Shotgun proteomics (166)
Bottom-up proteomics (79)
Data-independent acquisition (45)
Data-dependent acquisition (33)
Top-down proteomics (21)
Gel-based experiment (18)
Affinity purification coupled with mass spectrometry proteomics (15)
SWATH MS (12)
Mass spectrometry (10)
SRM/MRM (10)
DiaPASEF (9)
Mass spectrometry assay (8)
Mass spectrometry imaging (5)
ESI (3)
All-ion fragmentation (3)
HDMSE (3)
ILLUMINA, Illumina MiSeq (2)
NMR spectroscopy (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
NMR spectroscopy assay (1)
MSE (1)

Instrument Platform

Q Exactive (21)
Orbitrap Fusion Lumos (19)
Illumina NovaSeq 6000 (7)
Orbitrap Fusion (7)
Q Exactive HF (7)
Illumina HiSeq 2500 (5)
Illumina HiSeq 4000 (4)
NextSeq 500 (4)
Instrument (3)
BeadBug Benchtop homogenizer (2)
N/A (2)
NextSeq 2000 (2)
In-house built IMS-MS with Agilent TOF MS (2)
5-Laser BD FACSAria III (1)
Dell laptop (1)
Clariom D Human Transcriptome Arrays (Applied Biosystems, ThermoFisher) (1)
Thermal cycle, microcenrifuge, vortex mixer, pipettes (1)
Ionic purification system (Bionano Genomics) (1)
Microtome (1)
Biopsy punch (Ø 6 mm) and microtome (1)
10X Genomics Chromium (1)
None (1)
GeneChip Scanner 3000 7G (1)
ScanArray 5000 [PerkinElmer] (1)
Illumina NovaSeq X (1)
Illumina HiSeq 1000 (1)
NextSeq 550 (1)
Illumina HiSeq 2000 (1)
Illumina HiSeq 3000 (1)
Xevo G3 QTof (1)

Publication Date

2026 (185)
2025 (182)
2024 (143)
2023 (97)
2022 (84)
2021 (82)
2019 (61)
2020 (53)
2015 (45)
2016 (35)
2018 (33)
2017 (33)
2014 (31)
2013 (29)
2010 (20)
2012 (17)
2011 (16)
2008 (11)
2007 (9)
2009 (7)
2006 (5)
2005 (2)
2004 (1)

UNIPROT ID/AC

P05067 (6)
P08473 (2)
P50148 (2)
Q9NZ42 (2)
P56817 (2)
Q07954 (2)
P02649 (2)
P19174 (1)
P78352 (1)
Q13554 (1)
P50391 (1)
Q03169 (1)
P17861 (1)
Q13018 (1)
P04628 (1)
Q06787 (1)
P41221 (1)
Q14318 (1)
Q9Y618 (1)
P14324 (1)
O00755 (1)
P37268 (1)
O14936 (1)
O95388 (1)
P49768 (1)
P08069 (1)
P05019 (1)
P03372 (1)
P17655 (1)
Q9Y5W5 (1)

CHEBI ID

CHEBI:16761 (6)
CHEBI:15422 (6)
CHEBI:16027 (5)
CHEBI:17287 (4)
CHEBI:16015 (4)
CHEBI:29101 (3)
CHEBI:15361 (3)
CHEBI:18021 (3)
CHEBI:16908 (3)
CHEBI:64645 (2)
CHEBI:27354 (2)
CHEBI:37455 (2)
CHEBI:17634 (2)
CHEBI:26689 (2)
CHEBI:5656 (2)
CHEBI:16004 (2)
CHEBI:25523 (2)
CHEBI:17138 (2)
CHEBI:16113 (2)
CHEBI:25350 (2)
CHEBI:15531 (2)
CHEBI:11814 (2)
CHEBI:15351 (2)
CHEBI:48153 (2)
CHEBI:422 (2)
CHEBI:15379 (2)
CHEBI:48928 (2)
CHEBI:15721 (2)
CHEBI:16938 (2)
CHEBI:16474 (2)

Metabolite Name

Taurine (7)
Creatine (5)
Pseudouridine (5)
Hypoxanthine (5)
Guanosine (5)
Deoxycholic acid (4)
ATP (4)
DTMP (4)
Allantoin (4)
Carnosine (4)
Oxypurinol (4)
L-Glutamine (4)
Methylmalonic acid (4)
L-Valine (4)
Sucrose (4)
Serotonin (4)
Leucine (4)
Glutathione (4)
Uracil (4)
Ribitol (4)
Adenine (4)
Inosine (4)
Glyceric acid (4)
Adenosine diphosphate ribose (3)
Isocaproate (3)
Prostaglandin H2 (3)
Raloxifene (3)
5-Methoxytryptamine (3)
Anserine (3)
Glabranin (3)

First Public Date

2025 (158)
2024 (121)
2026 (115)
2023 (62)
2022 (46)
2021 (40)
2020 (36)
2014 (32)
2019 (29)
2018 (18)
2017 (16)
2015 (13)
2016 (9)
2013 (8)

Modelling Approach

Ordinary differential equation model (9)
Pharmacodynamics model (1)
Constraint-based model (1)

Lab affiliation

Department of Neurobiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA (11)
Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic (6)
Department of Molecular and Cellular Neurobiology, Center for Neurogenomics & Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands (5)
Division of Cardiovascular Sciences, School of Medical Science, Faculty of Biology, Medicine and Health, The University of Manchester (5)
St. Jude Children's Research Hospital (5)
DZNE Munich Neuroproteomics Feodor-Lynen Str. 17 81377 Munich Germany (3)
Department of Neurology, Yale School of Medicine, Yale University, new haven CT, USA (3)
Emory University School of Medicine Departments of Biochemistry and Neurology (3)
Federal University of Uberlandia (3)
National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (3)
The Drug Discovery Lab, Mary S. Easton Center for Alzheimer’s Disease Research, Department of Neurology, David Geffen School of Medicine, 710 Westwood Plaza, University of California Los Angeles, Los Angeles, CA 90095, USA (3)
University of Texas Medical Branch (3)
Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA (2)
Center for Neurogenomics and Cognitive Research, Department of Molecular and Cellular Neurobiology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands. (2)
Chronic Disease Programme (UFIEC), Instituto de Salud Carlos III, Majadahonda, E-28220 Madrid, Spain. (2)
Chronic Disease Programme, UFIEC, Instituto de Salud Carlos III, Majadahonda, E-28220 Madrid, Spain. (2)
DZNE Munich, Neuroproteomics, Feodor-Lynen-Str. 17, 81377 München, Germany (2)
Dalian Institute of Chemical Physics (2)
Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark (2)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (2)
Department of Chemistry and Biomolecular Chemistry, University of Wisconsin, Wisconsin, USA (2)
Department of Immunobiology, College of Life Science and Technology, Jinan University, Guangzhou, China. (2)
Department of Life and Environmental Sciences, University of Cagliari (2)
Department of Neuroscience of Disease, Brain Research Institute, Niigata University (2)
Department of Oncology-Pathology, Karolinska Institutet and Science for Life Laboratory, Stockholm, Sweden (2)
Department of Pharmacology and Chemical Biology Emory University (2)
Departments of Biochemistry and Neurology Emory University School of Medicine (2)
Emory University School of Medicine Department of Biochemistry (2)
Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361005, China (2)
Key Laboratory of Modern Toxicology of Shenzhen, Shenzhen Center for Disease Control and Prevention, No. 8, Longyuan Road, Nanshan District, Shenzhen, China 518055. (2)

IsPrivate

False (12)

Model Flag

Non Kinetic (1)

Modification

N6 (2)
N6-dimethyl-L-lysine (2)

Study type

Transcription profiling by array (123)
RNA-seq of coding RNA (19)
Methylation profiling by array (9)
Unknown experiment type (7)
Comparative genomic hybridization by array (4)
Proteomic profiling by array (4)
RNA-seq of total RNA (4)
RNA-seq of non coding RNA (4)
Animal - High-throughput sequencing (2)
MicroRNA profiling by high throughput sequencing (2)
ChIP-seq (2)
RNA-seq of coding RNA from single cells (2)
ChIP-chip by tiling array (1)
One-color microarray (1)
High-throughput sequencing (1)
Human - One-color microarray (1)
Single nucleus RNA sequencing (1)
DNA-seq (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2025 (3146)
2023 (2750)
2022 (2652)
2024 (2572)
2021 (2403)
2020 (1833)
2019 (1351)
2018 (1137)
2017 (941)
2016 (772)
2015 (672)
2014 (514)
2026 (401)
2013 (306)
2012 (288)
2011 (218)
2010 (177)
2009 (123)
2008 (75)
2007 (56)
2006 (34)
2004 (21)
2005 (18)
2003 (11)
2000 (7)
2002 (4)
1999 (4)
2001 (2)
1998 (2)
1997 (1)

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Urine metabolomics phenotyping and urinary biomarker exploratory in mild cognitive impairment and Alzheimer's disease.

INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

2024-01-11 | MTBLS8662 | MetaboLights

Cerebellum Alzheimer's Disease

Ion channel splice array data from cerebellum brain tissue samples collected from Alzheimer's disease patients. Temporal cortex (Alzheimer's disease affected brain tissue structure) and cerebellum (Alzheimer's disease unaffected brain tissue structure) samples from control subjects were compared to ...

ORGANISM(S): Homo sapiens

2010-06-11 | E-GEOD-6777 | biostudies-arrayexpress

Temporal Cortex Alzheimer's Disease

Ion channel splice array data from temporal cortex brain tissue samples collected from Alzheimer's disease patients. Temporal cortex (Alzheimer's disease affected brain tissue structure) and cerebellum (Alzheimer's disease unaffected brain tissue structure) samples from control subjects were compare...

ORGANISM(S): Homo sapiens

2010-06-11 | E-GEOD-6775 | biostudies-arrayexpress

Cerebellum Control (Alzheimer's disease control)

Ion channel splice array data from cerebellum brain tissue samples collected from control (non Alzheimer's disease) subjects. Temporal cortex (Alzheimer's disease affected brain tissue structure) and cerebellum (Alzheimer's disease unaffected brain tissue structure) samples from control subjects wer...

ORGANISM(S): Homo sapiens

2010-06-11 | E-GEOD-6778 | biostudies-arrayexpress

Temporal Cortex Control (Alzheimer's disease control)

Ion channel splice array data from temporal cortex brain tissue samples collected from control subjects (no Alzheimer's disease). Temporal cortex (Alzheimer's disease affected brain tissue structure) and cerebellum (Alzheimer's disease unaffected brain tissue structure) samples from control subjects...

ORGANISM(S): Homo sapiens

2010-06-11 | E-GEOD-6774 | biostudies-arrayexpress

Temporal lobe epilepsy and Alzheimer's disease

This SuperSeries is composed of the following subset Series: GSE6771: Temporal Cortex Control (mesial temporal lobe epilepsy control) GSE6773: Temporal neocortex mesial temporal lobe epilepsy GSE6774: Temporal Cortex Control (Alzheimer's disease control) GSE6775: Temporal Cortex Alzheimer's Disease ...

ORGANISM(S): Homo sapiens

2007-01-23 | E-GEOD-6834 | biostudies-arrayexpress

Determination and comparison of SCFAs in serum and colon content samples: Alzheimer's disease rat as a case study (Method validation)

SCFAs are the main microbial fermentation products from dietary fibers in colon and play a key role in keeping healthy in the whole-body. However, differences of SCFAs concentration in the serum and colon samples collected from rats had attracted few attentions. Here, we optimized the extract and...

2020-11-24 | MTBLS2146 | MetaboLights

Determination and comparison of SCFAs in serum and colon content samples: Alzheimer's disease rat as a case study (SCFA serum and colon content determination)

2020-11-24 | MTBLS2088 | MetaboLights

5-Hydroxymenthylation-associated Epigenetic Modifiers in Alzheimer's disease

Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized by progressive deterioration of cognitive function. Evidence suggests a role for epigenetic regulation, in particular the cytosine modifications 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC,) in AD. 5hmC is hi...

ORGANISM(S): Homo sapiens

2016-07-20 | E-GEOD-72782 | biostudies-arrayexpress

Exploring the effects of acupuncture intervention on the gut microbiota of SAMP8 mice, a model of Alzheimer's disease.

2026-02-26 | MTBLS13601 | MetaboLights

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INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

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