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ProteomicsThe AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts
Sporozoites and merozoites share a number of proteins that are expressed by both stages, including the Apical Membrane Antigen 1 (AMA1) and the Rhoptry Neck Proteins (RONs). Although AMA1 and RONs are essential for merozoite invasion of erythrocytes during asexual blood stage replication of the mala...
ORGANISM(S): Plasmodium berghei ANKA 
2022-08-12 | PXD031463 | Pride
Plasmodium Malaria Rons. Sporozoites Ama1 
ProteomicsSpo13/MEIKIN ensures a two-division meiosis by preventing the activation of APC/CAma1 at meiosis I
Genome haploidization at meiosis depends on two consecutive nuclear divisions, which are controlled by an oscillatory system consisting of Cdk1-cyclin B and the APC/C bound to the Cdc20 activator. How the oscillator generates exactly two divisions has been unclear. We have studied this question in y...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-09-03 | PXD044597 | Pride
Apc/c-ama1 / cyclin phosphorylation / meiotic exit / polo-like kinase / spo13/meikin / translational repressor 
UnknownNon-apical membrane antigen 1 (AMA1) IgGs from Malian children interfere with functional activity of AMA1 IgGs as judged by growth inhibition assay.
Not available
S-EPMC3113848 | biostudies-literature
UnknownIn vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic response.
Not available
S-EPMC133034 | biostudies-literature
UnknownStructure-based design of a strain transcending AMA1-RON2L malaria vaccine.
Not available
S-EPMC10475129 | biostudies-literature
UnknownBinding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion.
Not available
S-EPMC3156155 | biostudies-literature
UnknownImpact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians.
Not available
S-EPMC2013939 | biostudies-literature
UnknownStructure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody.
Not available
S-EPMC2323298 | biostudies-literature
UnknownDiversity covering AMA1-MSP119 fusion proteins as malaria vaccines.
Not available
S-EPMC3648017 | biostudies-literature
UnknownIdentification of adjuvants for clinical trials performed with Plasmodium falciparum AMA1 in rabbits.
Not available
S-EPMC6664700 | biostudies-literature
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